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Details on Person Mitochondrial fumarate hydratase (FH) tetramer catalyzes the...
| Class:Id | Summation:71412 |
|---|---|
| _displayName | Mitochondrial fumarate hydratase (FH) tetramer catalyzes the... |
| _timestamp | 2023-12-06 10:08:06 |
| modified | [InstanceEdit:198405] D'Eustachio, P, 2007-06-18 16:46:57 [InstanceEdit:451044] D'Eustachio, P, 2009-12-26 [InstanceEdit:9854201] Stephan, Ralf, 2023-11-23 [InstanceEdit:9855644] Stephan, Ralf, 2023-12-06 |
| text | Mitochondrial fumarate hydratase (FH) tetramer catalyzes the reversible reaction of fumarate and water to form malate, the seventh step of the TCA cycle (Ajalla Aleixo et al., 2019; Wang et al., 2020). Mutations in the FH gene can lead to fumarase deficiency (FMRD, MIM:606812) or to leiomyomatosis and renal cell cancer (HLRCC, MIM:150800) (Bourgeron et al., 1994; reviewed by Giallongo et al, 2023). |
| (summation) | [Reaction:70982] FH tetramer hydrates fumarate to L-malate [Homo sapiens] |
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No pathways have been reviewed or authored by Mitochondrial fumarate hydratase (FH) tetramer catalyzes the... (71412)
