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Details on Person PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate

Class:IdReaction:71296
_displayNamePGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate
_doReleaseTRUE
_timestamp2025-01-06 08:51:54
catalystActivity[CatalystActivity:71295] 6-phosphogluconolactonase activity of PGLS [cytosol]
catalystActivityReference[CatalystActivityReference:9643681] 6-phosphogluconolactonase activity of PGLS [cytosol] Identification of the cDNA encoding human 6-phosphogluconolactonase, the enzyme catalyzing the second step of the pentose phosphate pathway(1)
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:9934063] RHEA:12557
input[SimpleEntity:31467] D-Glucono-1,5-lactone 6-phosphate [cytosol]
[SimpleEntity:29356] H2O [cytosol]
internalReviewed[InstanceEdit:9926222] D'Eustachio, Peter, 2024-10-31
literatureReference[LiteratureReference:199813] Limiting role of 6-phosphogluconolactonase in erythrocyte hexose monophosphate pathway metabolism
[LiteratureReference:199812] Identification of the cDNA encoding human 6-phosphogluconolactonase, the enzyme catalyzing the second step of the pentose phosphate pathway(1)
modified[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:199798] D'Eustachio, P, 2007-07-12 14:26:41
[InstanceEdit:464972] D'Eustachio, P, 2010-01-24
[InstanceEdit:469645] D'Eustachio, P, 2010-01-25
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9925926] D'Eustachio, Peter, 2024-10-28
[InstanceEdit:9926221] D'Eustachio, Peter, 2024-10-31
[InstanceEdit:9927658] D'Eustachio, Peter, 2024-11-08
[InstanceEdit:9934059] Stephan, Ralf, 2025-01-06
namePGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate
D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate
output[SimpleEntity:29996] PDG [cytosol]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2004-07-06
reviewed[InstanceEdit:9927657] D'Eustachio, Peter, 2024-11-08
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:469644] D'Eustachio, P, 2010-01-24
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362044] R-HSA-71296.6
structureModified[InstanceEdit:9925926] D'Eustachio, Peter, 2024-10-28
summation[Summation:178632] Cytosolic 6-phosphogluconolactonase (PGLS) catalyzes the hyd...
(hasEvent)[Pathway:71336] Pentose phosphate pathway [Homo sapiens]
(precedingEvent)[Reaction:71299] PGD decarboxylates 6-phospho-D-gluconate [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790901] Update Tracker - [Reaction:71296] D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate - v32:[modifyText]
[_UpdateTracker:9792242] Update Tracker - [Reaction:71296] D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate - v22:[addLiteratureReference]
[_UpdateTracker:9928485] Update Tracker - [Reaction:71296] D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate - v91:[removeOutput]
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