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Details on Person 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+

Class:Id	Reaction:71239
_displayName	2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+
_doRelease	TRUE
_timestamp	2024-11-27 22:46:01
authored	[InstanceEdit:164915] D'Eustachio, P, 2005-07-20 13:46:37
catalystActivity	[CatalystActivity:71238] aminomuconate-semialdehyde dehydrogenase activity of AM-SHDH [cytosol]
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:9929689] RHEA:14470
edited	[InstanceEdit:164915] D'Eustachio, P, 2005-07-20 13:46:37
inferredFrom	[Reaction:164926] 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ [Felis catus]
input	[SimpleEntity:35181] 2AMA [cytosol] [SimpleEntity:29360] NAD+ [cytosol] [SimpleEntity:29356] H2O [cytosol]
literatureReference	[LiteratureReference:164916] Studies on the metabolism of the benzene ring of tryptophan in mammalian tissues. II. Enzymatic formation of alpha-muconic acid from 2-hydroxyanthranilic acid
modified	[InstanceEdit:113752] Schmidt, EE, 2004-06-21 10:53:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:164915] D'Eustachio, P, 2005-07-20 13:46:37 [InstanceEdit:517501] D'Eustachio, P, 2010-02-18 [InstanceEdit:565701] D'Eustachio, P, 2010-04-05 [InstanceEdit:1080815] D'Eustachio, P, 2010-11-27 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9929687] D'Eustachio, Peter, 2024-11-27
name	2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ 2-aminomuconate 6-semialdehyde + H2O + NAD(+) => (2Z,4E)-2-aminomuconate + 2 H(+) + NADH
output	[SimpleEntity:32913] 2AM [cytosol] [SimpleEntity:73473] NADH [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:71223] 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 [Homo sapiens] [Reaction:71218] 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359931] R-HSA-71239.4
summation	[Summation:164918] This reaction has been characterized in vitro using enzyme p...
(hasEvent)	[Pathway:71240] Tryptophan catabolism [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790474] Update Tracker - [Reaction:71239] 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ - v33:[addInput, addLiteratureReference, modifyText]
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