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Details on Person GSTZ1 isomerizes 4-MAA
Class:Id Reaction:71173
_displayName GSTZ1 isomerizes 4-MAA
_doRelease TRUE
_timestamp 2024-11-22 22:11:01
authored [InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
catalystActivity [CatalystActivity:71172] maleylacetoacetate isomerase activity of GSTZ1 dimer [cytosol]
catalystActivityReference [CatalystActivityReference:9643758] maleylacetoacetate isomerase activity of GSTZ1 dimer [cytosol] Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity
compartment [Compartment:70101] cytosol
crossReference [DatabaseIdentifier:9855284] RHEA:14818
edited [InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
input [SimpleEntity:31135] 4MAA [cytosol]
internalReviewed [InstanceEdit:9856173] D'Eustachio, Peter, 2023-12-13
literatureReference [LiteratureReference:71167] Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity [LiteratureReference:9855790] Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique [LiteratureReference:9855775] Preliminary X-ray crystallographic analysis of glutathione transferase zeta 1 (GSTZ1a-1a)
modified [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:517476] D'Eustachio, P, 2010-02-18 [InstanceEdit:1080814] D'Eustachio, P, 2010-11-27 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8963951] Jassal, Bijay, 2017-02-14 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9855286] Stephan, Ralf, 2023-12-01 [InstanceEdit:9855783] Stephan, Ralf, 2023-12-07 [InstanceEdit:9856170] Stephan, Ralf, 2023-12-13 [InstanceEdit:9929230] D'Eustachio, Peter, 2024-11-22
name GSTZ1 isomerizes 4-MAA 4-maleylacetoacetate => 4-fumarylacetoacetate maleylacetoacetate => fumarylacetoacetate
output [SimpleEntity:31175] 4FAA [cytosol]
precedingEvent
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360225] R-HSA-71173.7
summation [Summation:178945] Cytosolic maleylacetoacetic acid isomerase (MAAI, GSTZ1) cat...
(hasEvent) [Pathway:8963684] Tyrosine catabolism [Homo sapiens]
(precedingEvent) [Reaction:71181] FAH cleaves 4FAA [Homo sapiens]
(updatedInstance) [_UpdateTracker:9791182] Update Tracker - [Reaction:71173] maleylacetoacetate => fumarylacetoacetate - v32:[modifyText] [_UpdateTracker:9864340] Update Tracker - [Reaction:71173] GSTZ1 isomerizes 4-MAA - v88:[addLiteratureReference, modifyText]
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