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Details on Person FAD-SDHA [mitochondrial matrix]

Class:IdEntityWithAccessionedSequence:70983
_displayNameFAD-SDHA [mitochondrial matrix]
_timestamp2025-09-29 21:43:21
compartment[Compartment:5460] mitochondrial matrix
endCoordinate664
hasModifiedResidue[ModifiedResidue:9853508] 1'-(8alpha-FAD)-L-histidine at 99
literatureReference[LiteratureReference:9853493] The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein
modified[InstanceEdit:73784] Jassal, B, 2003-06-26 04:06:16
[InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08
[InstanceEdit:198405] D'Eustachio, P, 2007-06-18 16:46:57
[InstanceEdit:2167809] D'Eustachio, P, 2012-03-20
[InstanceEdit:9853494] Stephan, Ralf, 2023-11-16
[InstanceEdit:9854696] Stephan, Ralf, 2023-11-28
[InstanceEdit:9854978] Stephan, Ralf, 2023-11-29
[InstanceEdit:9967511] D'Eustachio, Peter, 2025-09-29
nameFAD-SDHA
Succinate Dehydrogenase complex subunit A
Succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial
Fp
Flavoprotein subunit of complex II
referenceEntity[ReferenceGeneProduct:53638] UniProt:P31040 SDHA [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:369403] R-HSA-70983.3
startCoordinate43
(activeUnit)[PositiveRegulation:9854700] Positive regulation by 'FUMA [mitochondrial matrix]'
[Requirement:9854702] Requirement by 'SDHAF2 [mitochondrial matrix]'
(hasComponent)[Complex:70984] SDHA:FAD [mitochondrial inner membrane] [Homo sapiens]
[Complex:70990] SDH complex [mitochondrial inner membrane] [Homo sapiens]
[Complex:70991] Succinate dehydrogenase flavoprotein (subunit A), reduced [mitochondrial inner membrane] [Homo sapiens]
[Complex:165640] Succinate dehydrogenase flavoprotein (subunit A) [mitochondrial inner membrane] [Homo sapiens]
[Complex:9854960] FAD-SDHA:SDHAF4 [mitochondrial matrix] [Homo sapiens]
[Complex:9855213] FAD-SDHA:SDHB:2Fe-2S:3Fe-4S:4Fe-4S:SDHFA1:SDHFA3 [mitochondrial matrix] [Homo sapiens]
(input)[Reaction:9854961] SDHAF4 binds to FAD-SDHA [Homo sapiens]
(output)[Reaction:9854672] FAD attaches to SDHA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9866381] Update Tracker - [EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] - v22:[modifyEndCoordinate, modifyStartCoordinate]
[_UpdateTracker:9872352] Update Tracker - [EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] - v41:[modifyName]
[_UpdateTracker:9972863] Update Tracker - [EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] - v95:[modifyStartCoordinate]
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No pathways have been reviewed or authored by FAD-SDHA [mitochondrial matrix] (70983)