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Details on Person FAD-SDHA [mitochondrial matrix]
Class:Id EntityWithAccessionedSequence:70983
_displayName FAD-SDHA [mitochondrial matrix]
_timestamp 2025-09-29 21:43:21
compartment [Compartment:5460] mitochondrial matrix
endCoordinate 664
hasModifiedResidue [ModifiedResidue:9853508] 1'-(8alpha-FAD)-L-histidine at 99
literatureReference [LiteratureReference:9853493] The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein
modified [InstanceEdit:73784] Jassal, B, 2003-06-26 04:06:16 [InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08 [InstanceEdit:198405] D'Eustachio, P, 2007-06-18 16:46:57 [InstanceEdit:2167809] D'Eustachio, P, 2012-03-20 [InstanceEdit:9853494] Stephan, Ralf, 2023-11-16 [InstanceEdit:9854696] Stephan, Ralf, 2023-11-28 [InstanceEdit:9854978] Stephan, Ralf, 2023-11-29 [InstanceEdit:9967511] D'Eustachio, Peter, 2025-09-29
name FAD-SDHA Succinate Dehydrogenase complex subunit A Succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial Fp Flavoprotein subunit of complex II
referenceEntity [ReferenceGeneProduct:53638] UniProt:P31040 SDHA [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:369403] R-HSA-70983.3
startCoordinate 43
(activeUnit) [PositiveRegulation:9854700] Positive regulation by 'FUMA [mitochondrial matrix]' [Requirement:9854702] Requirement by 'SDHAF2 [mitochondrial matrix]'
(hasComponent) [Complex:70984] SDHA:FAD [mitochondrial inner membrane] [Homo sapiens] [Complex:70990] SDH complex [mitochondrial inner membrane] [Homo sapiens] [Complex:70991] Succinate dehydrogenase flavoprotein (subunit A), reduced [mitochondrial inner membrane] [Homo sapiens] [Complex:165640] Succinate dehydrogenase flavoprotein (subunit A) [mitochondrial inner membrane] [Homo sapiens] [Complex:9854960] FAD-SDHA:SDHAF4 [mitochondrial matrix] [Homo sapiens] [Complex:9855213] FAD-SDHA:SDHB:2Fe-2S:3Fe-4S:4Fe-4S:SDHFA1:SDHFA3 [mitochondrial matrix] [Homo sapiens]
(input) [Reaction:9854961] SDHAF4 binds to FAD-SDHA [Homo sapiens]
(output) [Reaction:9854672] FAD attaches to SDHA [Homo sapiens]
(updatedInstance) [_UpdateTracker:9866381] Update Tracker - [EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] - v22:[modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9872352] Update Tracker - [EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] - v41:[modifyName] [_UpdateTracker:9972863] Update Tracker - [EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] - v95:[modifyStartCoordinate]
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