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Details on Person ACO2 isomerizes citrate

Class:IdReaction:70971
_displayNameACO2 isomerizes citrate
_doReleaseTRUE
_timestamp2024-02-15 20:40:25
catalystActivity[CatalystActivity:70969] aconitate hydratase activity of ACO2:4Fe-4S [mitochondrial matrix]
catalystActivityReference[CatalystActivityReference:9643553] aconitate hydratase activity of ACO2:4Fe-4S [mitochondrial matrix] Aconitase polymorphism in man
compartment[Compartment:5460] mitochondrial matrix
crossReference[DatabaseIdentifier:9854185] RHEA:10336
input[SimpleEntity:29654] CIT [mitochondrial matrix]
internalReviewed[InstanceEdit:9856153] D'Eustachio, Peter, 2023-12-12
literatureReference[LiteratureReference:198411] Purification and partial amino acid sequence of human aconitase
[LiteratureReference:450996] Aconitase polymorphism in man
[LiteratureReference:9853614] ACO2 clinicobiological dataset with extensive phenotype ontology annotation
modified[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:198405] D'Eustachio, P, 2007-06-18 16:46:57
[InstanceEdit:203945] Gopinathrao, G, 2007-11-19 17:27:54
[InstanceEdit:450991] D'Eustachio, P, 2009-12-24
[InstanceEdit:451028] D'Eustachio, P, 2009-12-26
[InstanceEdit:451044] D'Eustachio, P, 2009-12-26
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9853494] Stephan, Ralf, 2023-11-16
[InstanceEdit:9853615] Stephan, Ralf, 2023-11-17
[InstanceEdit:9854201] Stephan, Ralf, 2023-11-23
[InstanceEdit:9855645] Stephan, Ralf, 2023-12-06
[InstanceEdit:9856154] Stephan, Ralf, 2023-12-12
[InstanceEdit:9861237] D'Eustachio, Peter, 2024-02-15
nameACO2 isomerizes citrate
citrate => D-threo-isocitrate
output[SimpleEntity:29938] ISCIT [mitochondrial matrix]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
regulatedBy[NegativeRegulation:9855647] Negative regulation by 'ACO2:3Fe-4S [mitochondrial matrix]'
releaseDate2004-07-06
reviewed[InstanceEdit:9861215] Hill, David P, 2024-02-15
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:451045] D'Eustachio, P, 2009-12-26
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361457] R-HSA-70971.5
structureModified[InstanceEdit:9855645] Stephan, Ralf, 2023-12-06
summation[Summation:71415] Mitochondrial aconitase (ACO2) reversibly converts citrate t...
(hasEvent)[Pathway:71403] Citric acid cycle (TCA cycle) [Homo sapiens]
(precedingEvent)[Reaction:70967] IDH3 complex decarboxylates isocitrate [Homo sapiens]
[Reaction:450984] IDH2 dimer decarboxylates isocitrate [Homo sapiens]
(replacementInstances)[_Deleted:451030] Deletion of instance: 70970
(updatedInstance)[_UpdateTracker:9791193] Update Tracker - [Reaction:70971] citrate <=> isocitrate - v32:[addLiteratureReference, add_removeOutput, modifyText]
[_UpdateTracker:9792323] Update Tracker - [Reaction:70971] citrate <=> isocitrate - v22:[addLiteratureReference, modifyText]
[_UpdateTracker:9864269] Update Tracker - [Reaction:70971] ACO2 isomerizes citrate - v88:[addLiteratureReference, addRegulator, modifyText]
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