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Details on Person alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+

Class:IdReaction:70941
_displayNamealpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+
_doReleaseTRUE
_timestamp2025-07-11 17:15:03
authored[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
catalystActivity[CatalystActivity:508540] L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity of ALDH7A1 tetramer [mitochondrial matrix]
catalystActivityReference[CatalystActivityReference:9643397] L-aminoadipate-semialdehyde dehydrogenase activity of ALDH7A1 tetramer [mitochondrial matrix] Mutations in antiquitin in individuals with pyridoxine-dependent seizures
compartment[Compartment:5460] mitochondrial matrix
crossReference[DatabaseIdentifier:9929213] RHEA:12309
edited[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
input[SimpleEntity:113556] 2AMAS [mitochondrial matrix]
[SimpleEntity:113526] NAD+ [mitochondrial matrix]
[SimpleEntity:113521] H2O [mitochondrial matrix]
internalReviewed[InstanceEdit:9930750] D'Eustachio, Peter, 2024-12-05
literatureReference[LiteratureReference:508571] Mutations in antiquitin in individuals with pyridoxine-dependent seizures
[LiteratureReference:508537] Is antiquitin a mitochondrial Enzyme?
modified[InstanceEdit:113752] Schmidt, EE, 2004-06-21 10:53:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:508502] D'Eustachio, P, 2010-02-12
[InstanceEdit:508568] D'Eustachio, P, 2010-02-12
[InstanceEdit:517476] D'Eustachio, P, 2010-02-18
[InstanceEdit:975967] Jassal, Bijay, 2010-10-11
[InstanceEdit:1080818] D'Eustachio, P, 2010-11-27
[InstanceEdit:6783885] Jassal, Bijay, 2015-06-17
[InstanceEdit:6783886] Jassal, Bijay, 2015-06-17
[InstanceEdit:6788612] Jassal, Bijay, 2015-07-23
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9929230] D'Eustachio, Peter, 2024-11-22
[InstanceEdit:9930749] D'Eustachio, Peter, 2024-12-06
[InstanceEdit:9939374] D'Eustachio, Peter, 2025-02-25
[InstanceEdit:9960426] D'Eustachio, Peter, 2025-07-11
namealpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+
(S)-2-amino-6-oxohexanoate + H2O + NAD(+) => 2 H(+) + L-2-aminoadipate + NADH
output[SimpleEntity:508531] 2AMA [mitochondrial matrix]
[SimpleEntity:29362] NADH [mitochondrial matrix]
[SimpleEntity:113529] H+ [mitochondrial matrix]
[SimpleEntity:113529] H+ [mitochondrial matrix]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2004-07-06
reviewed[InstanceEdit:9939375] Hill, David P, 2025-02-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361704] R-HSA-70941.7
structureModified[InstanceEdit:9929230] D'Eustachio, Peter, 2024-11-22
summation[Summation:178459] Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) catal...
(hasEvent)[Pathway:71064] Lysine catabolism [Homo sapiens]
(precedingEvent)[Reaction:70952] alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790040] Update Tracker - [Reaction:70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - v35:[addInput]
[_UpdateTracker:9790866] Update Tracker - [Reaction:70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - v32:[addCatalystActivity, add_removeInput, add_removeLiteratureReference, add_removeOutput, modifyText]
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