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Details on Person alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2
Class:Id Reaction:70800 _displayName alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 _doRelease TRUE _timestamp 2024-08-02 17:57:01 catalystActivity [CatalystActivity:70798] acyl-CoA dehydrogenase activity of ACADSB tetramer [mitochondrial matrix] catalystActivityReference [CatalystActivityReference:9643583] acyl-CoA dehydrogenase activity of ACADSB tetramer [mitochondrial matrix] Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism compartment [Compartment:5460] mitochondrial matrix crossReference [DatabaseIdentifier:9917126] RHEA:43781 input [SimpleEntity:70718] 2MBUT-CoA [mitochondrial matrix] [SimpleEntity:113596] FAD [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix] internalReviewed [InstanceEdit:9917225] D'Eustachio, Peter, 2024-08-01 literatureReference [LiteratureReference:70801] Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism [LiteratureReference:70813] 2-Methylbutyryl-coenzyme A dehydrogenase deficiency: a new inborn error of L-isoleucine metabolism modified [InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:508267] D'Eustachio, P, 2010-02-11 [InstanceEdit:508376] D'Eustachio, P, 2010-02-11 [InstanceEdit:517476] D'Eustachio, P, 2010-02-18 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9907327] Stephan, Ralf, 2024-04-06 [InstanceEdit:9908873] Stephan, Ralf, 2024-04-23 [InstanceEdit:9917131] Stephan, Ralf, 2024-07-30 [InstanceEdit:9917363] D'Eustachio, Peter, 2024-08-02 name alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 output [SimpleEntity:70799] tiglyl-CoA [mitochondrial matrix] [SimpleEntity:31649] FADH2 [mitochondrial matrix] precedingEvent
previousReviewStatus [ReviewStatus:9821385] four stars releaseDate 2004-07-06 reviewed [InstanceEdit:9917333] Hill, David P, 2024-08-02 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:359751] R-HSA-70800.6 structureModified [InstanceEdit:9917131] Stephan, Ralf, 2024-07-30 summation [Summation:178469] Mitochondrial 2-methyl branched-chain acyl-CoA dehydrogenase... (hasEvent) [Pathway:70895] Branched-chain amino acid catabolism [Homo sapiens] (precedingEvent) [Reaction:70830] tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA [Homo sapiens] (updatedInstance) [_UpdateTracker:9790952] Update Tracker - [Reaction:70800] alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 - v32:[modifyText] [_UpdateTracker:9919411] Update Tracker - [Reaction:70800] alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 - v90:[modifyText, removeInput]
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No pathways have been reviewed or authored by alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (70800)
