Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person ornithine => putrescine + CO2

Class:IdReaction:70692
_displayNameornithine => putrescine + CO2
_doReleaseTRUE
_timestamp2025-11-21 18:38:25
authored[InstanceEdit:351144] Gopinathrao, G, 2008-05-21 15:52:50
catalystActivity[CatalystActivity:70691] ornithine decarboxylase activity of PXLP-K69-ODC1 dimer [cytosol]
catalystActivityReference[CatalystActivityReference:9955561] ornithine decarboxylase activity of PXLP-K69-ODC1 dimer [cytosol] Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:9955583] RHEA:22965
edited[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
input[SimpleEntity:29498] L-Orn [cytosol]
[SimpleEntity:70106] H+ [cytosol]
internalReviewed[InstanceEdit:9955817] D'Eustachio, Peter, 2025-06-11
literatureReference[LiteratureReference:9955578] Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding
[LiteratureReference:9955559] A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 1-amino-oxy-3-aminopropane
modified[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:354047] Gopinathrao, G, 2008-06-16 14:42:34
[InstanceEdit:354205] Gopinathrao, G, 2008-06-16 17:59:58
[InstanceEdit:354226] Gopinathrao, G, 2008-06-16 22:08:54
[InstanceEdit:377464] Gopinathrao, G, 2008-09-12 14:45:23
[InstanceEdit:377671] Gopinathrao, G, 2008-09-15 23:37:39
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9955584] D'Eustachio, Peter, 2025-06-10
[InstanceEdit:9955818] D'Eustachio, Peter, 2025-06-11
[InstanceEdit:9974435] D'Eustachio, Peter, 2025-11-21
nameornithine => putrescine + CO2
L-ornithine + H(+) => putrescine + CO2
output[SimpleEntity:29610] Putrescine [cytosol]
[SimpleEntity:113528] CO2 [cytosol]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2008-09-30
reviewed[InstanceEdit:377465] D'Eustachio, P, 2008-06-12 14:43:38
[InstanceEdit:9974434] D'Eustachio, Peter, 2025-11-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360627] R-HSA-70692.4
structureModified[InstanceEdit:9955584] D'Eustachio, Peter, 2025-06-10
summation[Summation:179017] L-ornithine is converted into putrescine by cytosolic ornith...
(hasEvent)[Pathway:351202] Metabolism of polyamines [Homo sapiens]
(precedingEvent)[Reaction:351215] Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine [Homo sapiens]
(updatedInstance)[_UpdateTracker:9791858] Update Tracker - [Reaction:70692] ornithine => putrescine + CO2 - v25:[modifyText]
[_UpdateTracker:9964627] Update Tracker - [Reaction:70692] ornithine => putrescine + CO2 - v94:[add_removeLiteratureReference, modifyText, removeInput]
[Change default viewing format]
No pathways have been reviewed or authored by ornithine => putrescine + CO2 (70692)
Follow Reactome