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Details on Person The dehydrogenation (oxidation) of proline to L-1-pyrroline-...

Class:IdSummation:70672
_displayNameThe dehydrogenation (oxidation) of proline to L-1-pyrroline-...
_timestamp2017-01-13 15:38:04
created[InstanceEdit:70671] 2003-03-13 00:00:00
modified[InstanceEdit:517454] D'Eustachio, P, 2010-02-18
[InstanceEdit:8955828] Jassal, Bijay, 2017-01-13
textThe dehydrogenation (oxidation) of proline to L-1-pyrroline-5-carboxylate coupled to the conversion of FAD to FADH2 is the first step in proline breakdown (Bender et al. 2005). Proline dehydrogenase (PRODH), the enzyme that catalyzes this reaction, is found in liver, kidney, and brain cells, where it is tightly bound to the inner mitochondrial membrane.
(summation)[Reaction:70670] PRODH oxidises L-Pro to 1PYR-5COOH [Homo sapiens]
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