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Details on Person OTC trimer [mitochondrial matrix]

Class:Id	Complex:70558
_displayName	OTC trimer [mitochondrial matrix]
_timestamp	2023-08-14 16:38:59
compartment	[Compartment:5460] mitochondrial matrix
hasComponent	[EntityWithAccessionedSequence:70557] OTC [mitochondrial matrix] [Homo sapiens] [EntityWithAccessionedSequence:70557] OTC [mitochondrial matrix] [Homo sapiens] [EntityWithAccessionedSequence:70557] OTC [mitochondrial matrix] [Homo sapiens]
literatureReference	[LiteratureReference:452023] Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes
modified	[InstanceEdit:452030] D'Eustachio, P, 2010-01-14 [InstanceEdit:517544] D'Eustachio, P, 2010-02-19 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9841800] D'Eustachio, Peter, 2023-08-14
name	OTC trimer ornithine transcarbamylase homotrimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:366169] R-HSA-70558.12
(normalEntity)	[EntityFunctionalStatus:9956526] loss_of_function of OTC variant trimers [mitochondrial matrix]
(output)	[BlackBoxEvent:9956502] OTC precursor is targeted to the mitochondrial matrix and processed [Homo sapiens]
(physicalEntity)	[CatalystActivity:70559] ornithine carbamoyltransferase activity of OTC trimer [mitochondrial matrix]
(updatedInstance)	[_UpdateTracker:9869072] Update Tracker - [Complex:70558] OTC trimer [mitochondrial matrix] - v32:[addLiteratureReference, addName]
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No pathways have been reviewed or authored by OTC trimer [mitochondrial matrix] (70558)