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Details on Person PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG

Class:IdReaction:70486
_displayNamePGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG
_doReleaseTRUE
_timestamp2025-01-01 11:07:11
catalystActivity[CatalystActivity:70485] phosphoglycerate kinase activity of PGK complexes [cytosol]
catalystActivityReference[CatalystActivityReference:9643186] phosphoglycerate kinase activity of PGK complexes [cytosol] Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:9933529] RHEA:14802
input[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:29728] 3PG [cytosol]
literatureReference[LiteratureReference:6808365] Characterization of phosphoglycerate kinase from human spermatozoa
[LiteratureReference:141486] Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence.
[LiteratureReference:141559] Complete amino acid sequence of human phosphoglycerate kinase. Isolation and amino acid sequence of tryptic peptides.
[LiteratureReference:450670] Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme
modified[InstanceEdit:74479] D'Eustachio, P, 2003-07-22 16:21:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:179493] D'Eustachio, P, 2006-05-04 15:59:15
[InstanceEdit:198480] D'Eustachio, P, 2007-06-22 14:17:01
[InstanceEdit:198534] D'Eustachio, P, 2007-06-22 15:53:40
[InstanceEdit:376871] D'Eustachio, P, 2008-09-10 19:02:07
[InstanceEdit:6809180] D'Eustachio, Peter, 2015-11-09
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9815667] D'Eustachio, Peter, 2022-08-25
[InstanceEdit:9815861] D'Eustachio, Peter, 2022-08-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
namePGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG
(2R)-3-phosphoglycerate + ATP => (2R)-3-phospho-glyceroyl phosphate + ADP
output[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29800] 1,3BPG [cytosol]
precedingEvent
releaseDate2004-07-06
reverseReaction
reviewed[InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12
[InstanceEdit:9815859] Hill, David P, 2022-08-29
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:6809179] D'Eustachio, Peter, 2015-11-09
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361764] R-HSA-70486.7
summation[Summation:71446] Cytosolic phosphoglycerate kinase (PGK) complexed with magne...
(hasEvent)[Pathway:70263] Gluconeogenesis [Homo sapiens]
(precedingEvent)[Reaction:70482] GAPDH tetramers reduce 1,3BPG to GA3P [Homo sapiens]
[Reaction:6798335] BPGM dimer isomerises 1,3BPG to 2,3BPG [Homo sapiens]
(reverseReaction)[Reaction:71850] PGK complexes dephosphorylate 1,3BPG [Homo sapiens]
(updatedInstance)[_UpdateTracker:9791765] Update Tracker - [Reaction:70486] ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate - v26:[modifyText]
[_UpdateTracker:9792278] Update Tracker - [Reaction:70486] ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate - v22:[addLiteratureReference, modifyText]
[_UpdateTracker:9846857] Update Tracker - [Reaction:70486] PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG - v83:[addLiteratureReference, modifyText]
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