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Details on Person GAPDH tetramers reduce 1,3BPG to GA3P
Class:Id Reaction:70482
_displayName GAPDH tetramers reduce 1,3BPG to GA3P
_doRelease TRUE
_timestamp 2025-01-01 11:04:59
catalystActivity [CatalystActivity:70448] glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity of GAPDH tetramers [cytosol]
catalystActivityReference [CatalystActivityReference:9644037] glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity of GAPDH tetramers [cytosol] Glyceraldehyde-3-phosphate dehydrogenase from human tissues
compartment [Compartment:70101] cytosol
crossReference [DatabaseIdentifier:9933518] RHEA:10302
input [SimpleEntity:29800] 1,3BPG [cytosol] [SimpleEntity:73473] NADH [cytosol] [SimpleEntity:70106] H+ [cytosol]
literatureReference [LiteratureReference:70433] Glyceraldehyde-3-phosphate dehydrogenase from human tissues [LiteratureReference:70436] Isozymes of glyceraldehyde 3-phosphate dehydrogenase in man and other mammals [LiteratureReference:70439] Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells [LiteratureReference:141459] Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene
modified [InstanceEdit:113752] Schmidt, EE, 2004-06-21 10:53:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:198480] D'Eustachio, P, 2007-06-22 14:17:01 [InstanceEdit:198534] D'Eustachio, P, 2007-06-22 15:53:40 [InstanceEdit:372822] D'Eustachio, P, 2008-07-03 22:07:04 [InstanceEdit:376871] D'Eustachio, P, 2008-09-10 19:02:07 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9815667] D'Eustachio, Peter, 2022-08-25 [InstanceEdit:9815861] D'Eustachio, Peter, 2022-08-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
name GAPDH tetramers reduce 1,3BPG to GA3P (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH => D-glyceraldehyde 3-phosphate + NAD(+) + phosphate
output [SimpleEntity:29578] GA3P [cytosol] [SimpleEntity:29372] Pi [cytosol] [SimpleEntity:29360] NAD+ [cytosol]
precedingEvent
releaseDate 2004-07-06
reverseReaction
reviewed [InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12 [InstanceEdit:9815859] Hill, David P, 2022-08-29
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:9815860] D'Eustachio, Peter, 2022-08-29
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360674] R-HSA-70482.6
summation [Summation:71447] The reversible reduction of 1,3BPG (1,3-bisphosphoglycerate)...
(hasEvent) [Pathway:70263] Gluconeogenesis [Homo sapiens]
(precedingEvent) [Reaction:70481] TPI1 dimer isomerizes GA3P to DHAP [Homo sapiens] [Reaction:71495] Aldolase tetramers convert GA3P and DHAP to F1,6PP [Homo sapiens]
(reverseReaction) [Reaction:70449] GADPH tetramer dehydrogenates GA3P [Homo sapiens]
(updatedInstance) [_UpdateTracker:9791726] Update Tracker - [Reaction:70482] 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ - v26:[modifyText] [_UpdateTracker:9792253] Update Tracker - [Reaction:70482] 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+ - v22:[addLiteratureReference, modifyText] [_UpdateTracker:9846824] Update Tracker - [Reaction:70482] GAPDH tetramers reduce 1,3BPG to GA3P - v83:[modifyText]
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