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Details on Person TPI1 dimer isomerizes GA3P to DHAP

Class:Id	Reaction:70481
_displayName	TPI1 dimer isomerizes GA3P to DHAP
_doRelease	TRUE
_timestamp	2025-01-01 11:08:06
catalystActivity	[CatalystActivity:70453] triose-phosphate isomerase activity of TPI1 dimer [cytosol]
catalystActivityReference	[CatalystActivityReference:9644044] triose-phosphate isomerase activity of TPI1 dimer [cytosol] Primary structure of human triosephosphate isomerase
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:9933536] RHEA:18586
input	[SimpleEntity:29578] GA3P [cytosol]
literatureReference	[LiteratureReference:141516] Molecular analysis of a series of alleles in humans with reduced activity at the triosephosphate isomerase locus [LiteratureReference:141467] Primary structure of human triosephosphate isomerase
modified	[InstanceEdit:141601] D'Eustachio, P, 2004-09-21 16:31:33 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:376871] D'Eustachio, P, 2008-09-10 19:02:07 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9815667] D'Eustachio, Peter, 2022-08-25 [InstanceEdit:9815861] D'Eustachio, Peter, 2022-08-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
name	TPI1 dimer isomerizes GA3P to DHAP D-glyceraldehyde 3-phosphate => dihydroxyacetone phosphate
output	[SimpleEntity:75970] DHAP [cytosol]
precedingEvent	[Reaction:70482] GAPDH tetramers reduce 1,3BPG to GA3P [Homo sapiens] [Reaction:70486] PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG [Homo sapiens]
releaseDate	2004-07-06
reverseReaction	[Reaction:70454] TPI1 dimer isomerizes DHAP to GA3P [Homo sapiens] [Reaction:70481] TPI1 dimer isomerizes GA3P to DHAP [Homo sapiens]
reviewed	[InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12 [InstanceEdit:9815859] Hill, David P, 2022-08-29
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9815860] D'Eustachio, Peter, 2022-08-29
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358890] R-HSA-70481.6
summation	[Summation:71448] The reversible conversion of GA3P (glyceraldehyde-3-phosphat...
(hasEvent)	[Pathway:70263] Gluconeogenesis [Homo sapiens]
(precedingEvent)	[Reaction:71495] Aldolase tetramers convert GA3P and DHAP to F1,6PP [Homo sapiens]
(reverseReaction)	[Reaction:70454] TPI1 dimer isomerizes DHAP to GA3P [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791741] Update Tracker - [Reaction:70481] D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate - v26:[modifyText] [_UpdateTracker:9792311] Update Tracker - [Reaction:70481] D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate - v22:[modifyText] [_UpdateTracker:9846843] Update Tracker - [Reaction:70481] TPI1 isomerizes GA3P to DHAP - v83:[modifyText]
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