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Details on Person GPI dimer isomerizes Fru(6)P to G6P

Class:IdReaction:70475
_displayNameGPI dimer isomerizes Fru(6)P to G6P
_doReleaseTRUE
_timestamp2025-01-01 11:05:19
authored[InstanceEdit:70327] Schmidt, EE, 2003-02-05 00:00:00
catalystActivity[CatalystActivity:70470] glucose-6-phosphate isomerase activity of GPI dimer [cytosol]
catalystActivityReference[CatalystActivityReference:9815658] glucose-6-phosphate isomerase activity of GPI dimer [cytosol] Enzymes of the human erythrocyte. IV. Phosphoglucose isomerase, purification and properties.
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:9933512] RHEA:11818
edited[InstanceEdit:376871] D'Eustachio, P, 2008-09-10 19:02:07
input[SimpleEntity:29512] Fru(6)P [cytosol]
literatureReference[LiteratureReference:141528] The characterization of gene mutations for human glucose phosphate isomerase deficiency associated with chronic hemolytic anemia
[LiteratureReference:141483] Enzymes of the human erythrocyte. IV. Phosphoglucose isomerase, purification and properties.
[Book:70473] The Enzymes, 3rd ed Boyer, PD Aldose-ketose isomerases 0121227022
modified[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:198480] D'Eustachio, P, 2007-06-22 14:17:01
[InstanceEdit:198551] D'Eustachio, P, 2007-06-22 16:17:09
[InstanceEdit:372872] D'Eustachio, P, 2008-07-08 18:05:57
[InstanceEdit:376871] D'Eustachio, P, 2008-09-10 19:02:07
[InstanceEdit:5662797] Orlic-Milacic, Marija, 2015-01-13
[InstanceEdit:5662798] Orlic-Milacic, Marija, 2015-01-13
[InstanceEdit:5674610] Orlic-Milacic, Marija, 2015-02-13
[InstanceEdit:8855814] Orlic-Milacic, Marija, 2016-02-05
[InstanceEdit:8979246] Orlic-Milacic, Marija, 2017-02-23
[InstanceEdit:9815667] D'Eustachio, Peter, 2022-08-25
[InstanceEdit:9815861] D'Eustachio, Peter, 2022-08-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
nameGPI dimer isomerizes Fru(6)P to G6P
beta-D-fructose 6-phosphate => alpha-D-glucose 6-phosphate
output[SimpleEntity:30537] G6P [cytosol]
precedingEvent
releaseDate2003-09-03
releaseStatusUPDATED
reverseReaction
reviewed[InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12
[InstanceEdit:9815859] Hill, David P, 2022-08-29
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:9815860] D'Eustachio, Peter, 2022-08-29
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359723] R-HSA-70475.6
summation[Summation:71503] The reversible isomerization of Fru(6)P (fructose-6-phosphat...
(hasEvent)[Pathway:70263] Gluconeogenesis [Homo sapiens]
[Pathway:5628897] TP53 Regulates Metabolic Genes [Homo sapiens]
(precedingEvent)[Reaction:70377] G6PD multimers dehydrogenate G6P [Homo sapiens]
[Reaction:198513] SLC7A4 exchanges G6P for Pi across the ER membrane [Homo sapiens]
[Reaction:8955760] PGM2L1:Mg2+ phosphorylates G6P to G1,6BP [Homo sapiens]
(reverseReaction)[Reaction:70471] GPI dimer isomerizes G6P [Homo sapiens]
(updatedInstance)[_UpdateTracker:9791781] Update Tracker - [Reaction:70475] D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate - v26:[modifyText]
[_UpdateTracker:9792289] Update Tracker - [Reaction:70475] D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate - v22:[addLiteratureReference, modifyText]
[_UpdateTracker:9846852] Update Tracker - [Reaction:70475] GPI dimer isomerizes Fru(6)P to G6P - v83:[modifyText]
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