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Details on Person The transfer of a high-energy phosphate bond from GTP to oxa...

Class:IdSummation:70242
_displayNameThe transfer of a high-energy phosphate bond from GTP to oxa...
_timestamp2022-08-25 14:42:46
modified[InstanceEdit:198534] D'Eustachio, P, 2007-06-22 15:53:40
[InstanceEdit:372822] D'Eustachio, P, 2008-07-03 22:07:04
[InstanceEdit:372872] D'Eustachio, P, 2008-07-08 18:05:57
[InstanceEdit:9815667] D'Eustachio, Peter, 2022-08-25
textThe transfer of a high-energy phosphate bond from GTP to oxaloacetate (OA), to form phosphoenolpyruvate (PEP), GDP, and CO2, is catalyzed by cytosolic phosphoenolpyruvate carboxykinase PCK1 (Dunten et al. 2002). This reaction is irreversible under physiological conditions.
(summation)[Reaction:70241] PCK1 phosphorylates OA to yield PEP [Homo sapiens]
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