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Details on Person UniProt:Q12798 CETN1
| Class:Id | ReferenceGeneProduct:69745 |
|---|---|
| _chainChangeLog | chain:1-172 added on Sat February 7 2015;chain:1-172 removed on Fri November 4 2016;initiator methionine:1 added on Fri November 4 2016;chain:2-172 added on Fri November 4 2016 |
| _displayName | UniProt:Q12798 CETN1 |
| _timestamp | 2024-11-03 19:55:37 |
| chain | chain:1-172 |
| checksum | 9ED8193F26F18881 |
| comment | FUNCTION Plays a fundamental role in microtubule-organizing center structure and function (PubMed:8175926). Plays a role in sperm cilia formation (By similarity).SUBUNIT Monomer (By similarity). Interacts with CIMAP3 (PubMed:20643351). Interacts with USP49 (PubMed:36702832).INTERACTION Centrosome of interphase and mitotic cells. In the retinal photoreceptor cells, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity).MISCELLANEOUS Binds two moles of calcium per mole of protein.SIMILARITY Belongs to the centrin family. |
| description | recommendedName: fullName evidence="8"Centrin-1 alternativeName: Caltractin isoform 2 |
| geneName | CETN1 CEN1 CETN |
| identifier | Q12798 |
| isSequenceChanged | FALSE |
| keyword | Calcium Cell cycle Cell division Cell projection Cytoplasm Cytoskeleton Metal-binding Mitosis Proteomics identification Reference proteome Repeat |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CETN1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996480] ENSEMBL:ENSG00000177143 CETN1 [Homo sapiens] |
| secondaryIdentifier | CETN1_HUMAN B2R536 |
| sequenceLength | 172 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:2161115] CETN1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9639700] CETN1 [cilium] [Homo sapiens] [EntityWithAccessionedSequence:9639714] Misfolded CETN1 [cilium] [Homo sapiens] [EntityWithAccessionedSequence:9640113] Misfolded CETN1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9641110] Ub-Misfolded CETN1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9641126] PolyUb-Misfolded CETN1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9659982] PolyUb-Misfolded CETN1 [late endosome lumen] [Homo sapiens] [EntityWithAccessionedSequence:9659990] PolyUb-Misfolded CETN1 [lysosomal lumen] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q12798 CETN1 (69745)
