Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person CDT1 binds geminin

Class:IdReaction:69299
_displayNameCDT1 binds geminin
_doReleaseTRUE
_timestamp2021-07-31 18:50:06
compartment[Compartment:7660] nucleoplasm
input[EntityWithAccessionedSequence:68536] CDT1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:113554] GMNN [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:68713] Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
[LiteratureReference:9749277] Geminin inhibits a late step in the formation of human pre-replicative complexes
modified[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:143525] Schmidt, EE, 2004-11-12 05:53:46
[InstanceEdit:156500] Schmidt, EE, 2004-11-17 09:36:09
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9749276] Orlic-Milacic, Marija, 2021-07-31
[InstanceEdit:9749282] Orlic-Milacic, Marija, 2021-07-31
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCDT1 binds geminin
output[Complex:156502] CDT1:GMNN [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360424] R-HSA-69299.4
summation[Summation:178532] Geminin (GMNN) tightly binds to CDT1 and inhibits CDT1-media...
(hasEvent)[Pathway:68962] Activation of the pre-replicative complex [Homo sapiens]
[Pathway:69052] Switching of origins to a post-replicative state [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775423] Update Tracker - [Reaction:69299] CDT1 binds geminin - v79:[modifyText]
[_UpdateTracker:9775582] Update Tracker - [Reaction:69299] CDT1 binds geminin - v78:[addLiteratureReference, modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by CDT1 binds geminin (69299)