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Details on Person Rapid destruction of human Cdc25A in response to DNA damage.

Class:IdLiteratureReference:69264
_displayNameRapid destruction of human Cdc25A in response to DNA damage.
_timestamp2006-05-18 18:57:10
author[Person:69265] Mailand, N
[Person:69267] Lukas, C
[Person:77147] Syljuâsen, RG
[Person:69269] Welcker, M
[Person:68709] Lukas, J
journalScience
modified[InstanceEdit:180186] D'Eustachio, P, 2006-05-16 19:38:33
[InstanceEdit:180389] D'Eustachio, P, 2006-05-18 18:57:06
[InstanceEdit:180389] D'Eustachio, P, 2006-05-18 18:57:06
pages1425-9
pubMedIdentifier10827953
titleRapid destruction of human Cdc25A in response to DNA damage.
volume288
year2000
(literatureReference)[Summation:69605]

DNA damage caused by ultraviolet light (UV), ionizing rad...
[Summation:69612] In response to DNA damage due to exposure to ultraviolet (UV...
[Summation:69614]

The G1/S arrest induced by DNA damage has been ascribed t...
[Summation:179124]

Exposure of various human cell lines to ultraviolet (UV) ...
[Summation:179284]

Exposure of various human cell lines to ultraviolet (UV) ...
[Summation:212961]

CDC25A protein, a phosphatase required for progression fr...
[Reaction:69598] Ubiquitination of phosphorylated CDC25A [Homo sapiens]
[BlackBoxEvent:69600] Proteolytic degradation of ubiquitinated-Cdc25A [Homo sapiens]
[Pathway:69601] Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A [Homo sapiens]
[Reaction:69604] Phosphorylation of CDC25A by CHEK1 [Homo sapiens]

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