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Details on Person Formation of Cyclin E:Cdk2 complexes

Class:Id	Reaction:69191
_displayName	Formation of Cyclin E:Cdk2 complexes
_doRelease	TRUE
_timestamp	2017-02-06 15:23:44
compartment	[Compartment:70101] cytosol
figure	[Figure:72786] /figures/cycline_cdk2.jpg
input	[EntityWithAccessionedSequence:157440] CDK2 [cytosol] [Homo sapiens] [DefinedSet:157462] CCNE [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:77499] Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2.
modified	[InstanceEdit:72785] Joshi-Tope, G, 2003-06-12 05:55:26 [InstanceEdit:77491] Matthews, L, 0000-00-00 00:00:00 [InstanceEdit:113655] Gopinathrao, G, 2004-06-14 19:10:00 [InstanceEdit:157593] Matthews, L, 2005-01-04 10:09:56 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:188370] Matthews, L, 2006-10-10 13:55:54 [InstanceEdit:692407] Matthews, L, 2010-05-07 [InstanceEdit:736072] Matthews, L, 2010-05-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8961851] Orlic-Milacic, Marija, 2017-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of Cyclin E:Cdk2 complexes
output	[Complex:157594] CCNE:CDK2 [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:8961846] CCNE1 gene transcription is stimulated by E2F1 [Homo sapiens] [Reaction:8961840] E2F1 binds the CCNE1 gene promoter [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:188346] Matthews, L, 2006-10-10 08:05:07
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359010] R-HSA-69191.4
summation	[Summation:69192] The E-type cyclins and Cyclin-Dependent Kinase 2 control the...
(hasEvent)	[Pathway:69202] Cyclin E associated events during G1/S transition [Homo sapiens]
(precedingEvent)	[Reaction:157906] Translocation of Cyclin E:Cdk2 complex to the nucleus [Homo sapiens]
(replacementInstances)	[_Deleted:737638] Deletion of instance: 69635 [_Deleted:737643] Deletion of instance: 69637
(updatedInstance)	[_UpdateTracker:9953616] Update Tracker - [Reaction:69191] Formation of Cyclin E:Cdk2 complexes - v93:[modifyText]
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No pathways have been reviewed or authored by Formation of Cyclin E:Cdk2 complexes (69191)