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Details on Person Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are...
| Class:Id | Summation:69167 |
|---|---|
| _displayName | Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are... |
| _timestamp | 2017-04-06 15:48:47 |
| literatureReference | [LiteratureReference:69057] Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. |
| modified | [InstanceEdit:1458580] D'Eustachio, P, 2011-07-21 [InstanceEdit:1458581] D'Eustachio, P, 2011-07-21 [InstanceEdit:8984457] Duenas, Corina, 2017-04-06 |
| text | Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure (Tsurimoto and Stillman 1991). The Dna2 endonuclease/helicase in yeast is a monomer of approximately 172 kDa. Human FEN-1 is a single polypeptide of approximately 42 kDa. Replication Protein A regulates the switching of endonucleases during the removal of the displaced flap (Tsurimoto et al.1991). |
| (summation) | [Pathway:69166] Removal of the Flap Intermediate [Homo sapiens] [Pathway:174437] Removal of the Flap Intermediate from the C-strand [Homo sapiens] |
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No pathways have been reviewed or authored by Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are... (69167)
