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Details on Person Formation of Okazaki fragments
Class:Id Reaction:69116
_displayName Formation of Okazaki fragments
_doRelease TRUE
_timestamp 2017-12-07 06:44:55
catalystActivity [CatalystActivity:69115] DNA-directed DNA polymerase activity of DNA Polymerase delta tetramer [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
input [Complex:68451] Processive complex [nucleoplasm] [Homo sapiens]
literatureReference [LiteratureReference:69118] Reconstitution of complete SV40 DNA replication with purified replication factors. [LiteratureReference:69076] Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1. [LiteratureReference:69080] Interaction of proliferating cell nuclear antigen with yeast DNA polymerase delta. [LiteratureReference:69121] Enzymes and reactions at the eucaryotic DNA replication fork. [LiteratureReference:69123] Assembly of simian virus 40 Okazaki pieces from DNA primers is reversibly arrested by ATP depletion. [LiteratureReference:69057] Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis.
modified [InstanceEdit:143525] Schmidt, EE, 2004-11-12 05:53:46 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:200278] D'Eustachio, P, 2007-07-16 20:47:41 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9032177] Orlic-Milacic, Marija, 2017-12-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Formation of Okazaki fragments
output [Complex:68453] Processive complex:Okazaki fragment complex [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:359247] R-HSA-69116.4
summation [Summation:69117] After RFC initiates the assembly of the primer recognition c...
(hasEvent) [Pathway:69183] Processive synthesis on the lagging strand [Homo sapiens]
(inferredFrom) [Reaction:1113082] Formation of Okazaki fragments [Oryza sativa]
(orthologousEvent) [Reaction:1113082] Formation of Okazaki fragments [Oryza sativa]
(precedingEvent) [Reaction:69127] Formation of the Flap Intermediate [Homo sapiens]
(updatedInstance) [_UpdateTracker:9777236] Update Tracker - [Reaction:69116] Formation of Okazaki fragments - v72:[modifyText] [_UpdateTracker:9792275] Update Tracker - [Reaction:69116] Formation of Okazaki fragments - v22:[addLiteratureReference]
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No pathways have been reviewed or authored by Formation of Okazaki fragments (69116)