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Details on Person Cdc6 protein is phosphorylated by CDK

Class:IdReaction:69005
_displayNameCdc6 protein is phosphorylated by CDK
_doReleaseTRUE
_timestamp2021-08-03 16:24:23
catalystActivity[CatalystActivity:9032216] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
input[EntityWithAccessionedSequence:68542] CDC6 [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
literatureReference[LiteratureReference:68381] Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6
modified[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:143525] Schmidt, EE, 2004-11-12 05:53:46
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671733] D'Eustachio, P, 2012-11-23
[InstanceEdit:5661318] D'Eustachio, Peter, 2015-01-10
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9032215] Orlic-Milacic, Marija, 2017-12-07
[InstanceEdit:9749431] Matthews, Lisa, 2021-08-03
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCdc6 protein is phosphorylated by CDK
output[EntityWithAccessionedSequence:5661317] p-CDC6 [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360504] R-HSA-69005.5
summation[Summation:178530] At the beginning of this reaction, 1 molecule of 'CDC6', and...
(hasEvent)[Pathway:69017] CDK-mediated phosphorylation and removal of Cdc6 [Homo sapiens]
(precedingEvent)[Reaction:69006] Phosphorylated Cdc6 is exported from the nucleus [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779941] Update Tracker - [Reaction:69005] Cdc6 protein is phosphorylated by CDK - v64:[add_removeCatalystActivity]
[_UpdateTracker:9785388] Update Tracker - [Reaction:69005] Cdc6 protein is phosphorylated by CDK - v52:[add_removeOutput]
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