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Details on Person DNA polymerase epsilon binds at the origin

Class:Id	Reaction:68960
_displayName	DNA polymerase epsilon binds at the origin
_doRelease	TRUE
_timestamp	2016-11-10 00:55:35
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:68951] Davey, MJ, O'Donnell, M, 2003-06-05 08:03:13
input	[Complex:68483] DNA polymerase epsilon [nucleoplasm] [Homo sapiens] [OtherEntity:68419] origin of replication [nucleoplasm]
literatureReference	[LiteratureReference:68941] DNA replication in eukaryotic cells
modified	[InstanceEdit:111625] Joshi-Tope, G, 2004-03-03 09:38:49 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DNA polymerase epsilon binds at the origin
output	[Complex:68485] DNA polymerase epsilon:origin complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:68916] DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin [Homo sapiens] [Reaction:68917] Cdc45 associates with the pre-replicative complex at the origin [Homo sapiens]
regulatedBy	[PositiveRegulation:68961] Positive regulation by 'CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm]'
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360462] R-HSA-68960.4
summation	[Summation:178693] At the beginning of this reaction, 1 molecule of 'origin of ...
(hasEvent)	[Pathway:68962] Activation of the pre-replicative complex [Homo sapiens]
(inferredFrom)	[Reaction:1113084] DNA polymerase epsilon binds at the origin [Oryza sativa]
(orthologousEvent)	[Reaction:1113084] DNA polymerase epsilon binds at the origin [Oryza sativa]
(precedingEvent)	[Reaction:68914] DNA polymerase alpha:primase binds at the origin [Homo sapiens]
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No pathways have been reviewed or authored by DNA polymerase epsilon binds at the origin (68960)