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Details on Person Ubiquitinated Orc1 enters the cytosol

Class:Id	Reaction:68947
_displayName	Ubiquitinated Orc1 enters the cytosol
_doRelease	TRUE
_timestamp	2017-12-07 15:03:03
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
input	[EntityWithAccessionedSequence:9032189] PolyUb,p-S,T-ORC1 [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:68612] Mammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle
modified	[InstanceEdit:113652] Schmidt, EE, 2004-06-11 08:58:20 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2666270] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9032193] Orlic-Milacic, Marija, 2017-12-07 [InstanceEdit:9032197] Orlic-Milacic, Marija, 2017-12-07 [InstanceEdit:9032206] Orlic-Milacic, Marija, 2017-12-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ubiquitinated Orc1 enters the cytosol
output	[EntityWithAccessionedSequence:9032195] PolyUb,p-S,T-ORC1 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:68946] Phosphorylated Orc1 is ubiquitinated while still associated with chromatin [Homo sapiens] [Reaction:68944] Orc1 is phosphorylated by cyclin A/CDK2 [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360393] R-HSA-68947.4
summation	[Summation:179280] Ubiquitinated ORC1 translocates to the cytosol (Li and DePam...
(hasEvent)	[Pathway:68949] Orc1 removal from chromatin [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:68948] Ubiquitinated Orc1 is degraded by the proteasome [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780063] Update Tracker - [Reaction:68947] Ubiquitinated Orc1 enters the cytosol - v64:[add_removeInput, add_removeLiteratureReference, add_removeOutput, modifyText]
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