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Details on Person Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7

Class:Id	Reaction:68919
_displayName	Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7
_doRelease	TRUE
_timestamp	2016-11-10 00:55:42
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:68951] Davey, MJ, O'Donnell, M, 2003-06-05 08:03:13
input	[Complex:68559] pre-replicative complex [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:68403] MCM10 [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:68920] The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase
modified	[InstanceEdit:111625] Joshi-Tope, G, 2004-03-03 09:38:49 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:169517] Gopinathrao, G, 2005-11-29 21:05:54 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9768319] Orlic-Milacic, Marija, 2022-03-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7
output	[Complex:68560] MCM10:pre-replicative complex [nucleoplasm] [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359405] R-HSA-68919.4
summation	[Summation:68930] MCM10 is required for human DNA replication. In S. cerevisia...
(hasEvent)	[Pathway:68962] Activation of the pre-replicative complex [Homo sapiens]
(inferredFrom)	[Reaction:1113078] Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 [Oryza sativa]
(orthologousEvent)	[Reaction:1113078] Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 [Oryza sativa]
(precedingEvent)	[Reaction:68940] Cdt1 is displaced from the pre-replicative complex [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9788874] Update Tracker - [Reaction:68919] Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 - v40:[modifyText]
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No pathways have been reviewed or authored by Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (68919)