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Details on Person The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin

Class:IdReaction:68913
_displayNameThe primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin
_doReleaseTRUE
_timestamp2021-11-04 22:29:31
catalystActivity[CatalystActivity:68509] DNA-directed RNA polymerase activity of DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
input[Complex:68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] [Homo sapiens]
[SimpleEntity:9757634] NTP [nucleoplasm]
literatureReference[LiteratureReference:69330] DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha
modified[InstanceEdit:72785] Joshi-Tope, G, 2003-06-12 05:55:26
[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:163124] Joshi-Tope, G, 2005-04-18 14:31:09
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:164598] Gopinathrao, G, 2005-06-02 18:47:53
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9749431] Matthews, Lisa, 2021-08-03
[InstanceEdit:9757788] D'Eustachio, Peter, 2021-11-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameThe primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin
output[Complex:68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] [Homo sapiens]
[Complex:68483] DNA polymerase epsilon [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359227] R-HSA-68913.5
summation[Summation:179202] At the beginning of this reaction, 1 molecule of 'DNA polyme...
(hasEvent)[Pathway:68952] DNA replication initiation [Homo sapiens]
(inferredFrom)[Reaction:1113079] The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin [Oryza sativa]
(orthologousEvent)[Reaction:1113079] The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin [Oryza sativa]
(precedingEvent)[Reaction:68950] The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin [Homo sapiens]
[Reaction:9710480] Decitabine triphosphate incorporates into DNA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775315] Update Tracker - [Reaction:68913] The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin - v79:[add_removeInput]
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