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Details on Person Formation of ORC(1-6) complex
Class:Id Reaction:68615
_displayName Formation of ORC(1-6) complex
_doRelease TRUE
_timestamp 2021-08-17 01:28:11
authored [InstanceEdit:68951] Davey, MJ, O'Donnell, M, 2003-06-05 08:03:13
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:68951] Davey, MJ, O'Donnell, M, 2003-06-05 08:03:13
edited [InstanceEdit:9750784] Orlic-Milacic, Marija, 2021-08-16
input [Complex:9749104] ORC(1-5):origin of replication [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9734715] p-T195-ORC6 [nucleoplasm] [Homo sapiens]
literatureReference [LiteratureReference:9734659] Assembly of the human origin recognition complex occurs through independent nuclear localization of its components [LiteratureReference:9735417] Genetic analysis of human Orc2 reveals specific domains that are required in vivo for assembly and nuclear localization of the origin recognition complex [LiteratureReference:9749207] Drosophila model of Meier-Gorlin syndrome based on the mutation in a conserved C-Terminal domain of Orc6
modified [InstanceEdit:111625] Joshi-Tope, G, 2004-03-03 09:38:49 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:176962] Gopinathrao, G, 2006-03-17 19:09:52 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9750798] Orlic-Milacic, Marija, 2021-08-16 [InstanceEdit:9750805] Orlic-Milacic, Marija, 2021-08-16 [InstanceEdit:9750923] Orlic-Milacic, Marija, 2021-08-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Formation of ORC(1-6) complex
output [Complex:9749111] ORC(1-6):origin of replication [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:9750793] Kusic-Tisma, Jelena, 2021-07-30
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:359657] R-HSA-68615.4
summation [Summation:9749115] ORC6 associates with the ORC(1-5) complex to form the ORC(1-...
(hasEvent) [Pathway:68616] Assembly of the ORC complex at the origin of replication [Homo sapiens] [Pathway:9734667] (NEW) Assembly of the ORC complex at the origin of replication [Homo sapiens]
(inferredFrom) [Reaction:1113080] Orc6 associates with Orc1:Orc4:Orc5:Orc3:Orc2:origin complexes, forming ORC:origin complexes [Oryza sativa]
(orthologousEvent) [Reaction:1113080] Orc6 associates with Orc1:Orc4:Orc5:Orc3:Orc2:origin complexes, forming ORC:origin complexes [Oryza sativa]
(precedingEvent) [Reaction:113638] Association of Cyclin B/Cdk1 with replicative origin inhibits pre-RC formation [Homo sapiens]
(updatedInstance) [_UpdateTracker:9775671] Update Tracker - [Reaction:68615] Formation of ORC(1-6) complex - v78:[add_removeInput, add_removeLiteratureReference, add_removeOutput, add_removeSummation]
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