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Details on Person UniProt:P51959 CCNG1
| Class:Id | ReferenceGeneProduct:68593 |
|---|---|
| _chainChangeLog | chain:1-295 added on Fri February 6 2015 |
| _displayName | UniProt:P51959 CCNG1 |
| _timestamp | 2024-11-03 19:40:16 |
| chain | chain:1-295 |
| checksum | EA0B02C83F3B6BF3 |
| comment | FUNCTION May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).INTERACTION DNA replication foci after DNA damage.ALTERNATIVE PRODUCTS High levels in skeletal muscle, ovary, kidney and colon.DEVELOPMENTAL STAGE Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.INDUCTION Activated in breast and prostate cancer cells. Activated by actinomycin-D induced DNA damage.SIMILARITY Belongs to the cyclin family. Cyclin G subfamily. |
| description | recommendedName: Cyclin-G1 shortName: Cyclin-G |
| geneName | CCNG1 CCNG CYCG1 |
| identifier | P51959 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cell cycle Cell division Cyclin Mitosis Nucleus Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CCNG1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:6791398] ENSEMBL:ENSG00000113328 CCNG1 [Homo sapiens] |
| secondaryIdentifier | CCNG1_HUMAN B2R7B2 B4DLW7 D3DQK7 Q15757 Q96L32 |
| sequenceLength | 295 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8973206] UniProt:P51959-1 CCNG1 [Homo sapiens] [ReferenceIsoform:8973207] UniProt:P51959-2 CCNG1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:6792489] CCNG1 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P51959 CCNG1 (68593)
