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Details on Person ORC1 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:68522
_displayName ORC1 [nucleoplasm]
_timestamp 2013-05-03 18:44:28
compartment [Compartment:7660] nucleoplasm
endCoordinate 861
modified [InstanceEdit:73680] Gillespie, ME, 0000-00-00 00:00:00 [InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06 [InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08 [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3322333] Wu, G, 2013-05-03 [InstanceEdit:3322334] Wu, G, 2013-05-03
name ORC1 Orc1 Origin recognition complex subunit 1 Replication control protein 1
referenceEntity [ReferenceGeneProduct:97385] UniProt:Q13415 ORC1 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:370154] R-HSA-68522.2
startCoordinate 1
(hasComponent) [Complex:68540] ORC:origin of replication [nucleoplasm] [Homo sapiens] [Complex:68592] Orc1:Orc4:Orc5:Orc3:Orc2:origin [nucleoplasm] [Homo sapiens] [Complex:176958] ORC complex bound to origin [nucleoplasm] [Homo sapiens] [Complex:9736362] ORC(1-5) [nucleoplasm] [Homo sapiens] [Complex:9749101] ORC1:origin of replication [nucleoplasm] [Homo sapiens] [Complex:9749192] ORC1:H4K20Me2-nucleosome [nucleoplasm] [Homo sapiens] [Complex:9988290] HHV8 DNA:LANA1:ORC complex [nucleoplasm] [Homo sapiens] [Complex:9988318] HHV8 DNA:LANA1:ORC complex:CDC6 [nucleoplasm] [Homo sapiens] [Complex:9988329] HHV8 DNA:LANA1:ORC complex:CDC6:CDT1 [nucleoplasm] [Homo sapiens] [Complex:9988431] HHV8 DNA:pre-RC [nucleoplasm] [Homo sapiens]
(hasMember) [CandidateSet:480118] E2F activated proteins (nuclear) [nucleoplasm] [Homo sapiens] [DefinedSet:500385] Proteins Encoded by Genes Activated by OCT4:SOX2:NANOG [nucleoplasm] [Homo sapiens] [CandidateSet:539110] E2F1 targets [nucleoplasm] [Homo sapiens]
(inferredFrom) [DefinedSet:1113324] Homologues of Orc1 [nucleoplasm] [Oryza sativa] [EntityWithAccessionedSequence:1113996] Q5SMU7 [nucleoplasm] [Oryza sativa]
(input) [Reaction:9749098] ORC1 binds to DNA at origin of replication sites [Homo sapiens] [Reaction:9749197] ORC1 binds to H4K20me2 [Homo sapiens] [BlackBoxEvent:9988298] LANA1 at TR recruits ORC complex [Homo sapiens]
(output) [BlackBoxEvent:113632] Expression of ORC1 [Homo sapiens] [BlackBoxEvent:2889034] Expression of ORC1 in Stem Cells [Homo sapiens] [BlackBoxEvent:8961678] ORC1 gene expression is stimulated by E2F1 [Homo sapiens] [BlackBoxEvent:9734730] ORC1 translocates to the nucleus [Homo sapiens] [BlackBoxEvent:9988750] Replisome disassembles [Homo sapiens]
(updatedInstance) [_UpdateTracker:9880167] Update Tracker - [EntityWithAccessionedSequence:68522] ORC1 [nucleoplasm] - v44:[modifyEndCoordinate] [_UpdateTracker:9881127] Update Tracker - [EntityWithAccessionedSequence:68522] ORC1 [nucleoplasm] - v45:[addName]
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Pathways
No pathways have been reviewed or authored by ORC1 [nucleoplasm] (68522)