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Details on Person DNA polymerase alpha:primase [nucleoplasm]

Class:IdComplex:68507
_displayNameDNA polymerase alpha:primase [nucleoplasm]
_timestamp2019-11-29 18:10:45
compartment[Compartment:7660] nucleoplasm
hasComponent
literatureReference[LiteratureReference:68488] Eukaryotic DNA polymerases
[LiteratureReference:9668807] The C-terminal domain of the DNA polymerase catalytic subunit regulates the primase and polymerase activities of the human DNA polymerase α-primase complex
modified[InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06
[InstanceEdit:183145] Gillespie, ME, 2006-07-21 18:37:18
[InstanceEdit:9668820] Orlic-Milacic, Marija, 2019-11-29
nameDNA polymerase alpha:primase
DNA Pol alpha:primase
primosome
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:370513] R-HSA-68507.2
(activeUnit)[CatalystActivity:68509] DNA-directed RNA polymerase activity of DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm]
[CatalystActivity:8964437] DNA-directed RNA polymerase activity of DNA polymerase alpha:primase:DNA polymerase alpha:G-strand extended telomere end [nucleoplasm]
[CatalystActivity:9668596] DNA-directed DNA polymerase activity of RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm]
(hasComponent)[Complex:68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] [Homo sapiens]
[Complex:68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] [Homo sapiens]
[Complex:174434] RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] [Homo sapiens]
[Complex:174473] DNA polymerase alpha:primase:DNA polymerase alpha:G-strand extended telomere end [nucleoplasm] [Homo sapiens]
[Complex:9668602] POLA:primase:G-strand extended telomere end [nucleoplasm] [Homo sapiens]
(inferredFrom)[Complex:1115034] DNA polymerase alpha:primase (name copied from entity in Homo sapiens) [nucleoplasm] [Oryza sativa]
(input)[Reaction:68914] DNA polymerase alpha:primase binds at the origin [Homo sapiens]
[Reaction:9668597] DNA polymerase:primase binds G-strand of the telomere [Homo sapiens]
(output)[Reaction:113504] Detection of damage during initiation of DNA synthesis in S-phase [Homo sapiens]
[Reaction:174452] RFC binding displaces Pol Alpha on the C-strand of the telomere [Homo sapiens]
(physicalEntity)[CatalystActivity:68508] DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
(updatedInstance)[_UpdateTracker:9901054] Update Tracker - [Complex:68507] DNA polymerase alpha:primase [nucleoplasm] - v72:[addLiteratureReference, add_removeHasComponent]
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No pathways have been reviewed or authored by DNA polymerase alpha:primase [nucleoplasm] (68507)