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Details on Person RPA heterotrimer [nucleoplasm]
Class:Id Complex:68462
_displayName RPA heterotrimer [nucleoplasm]
_timestamp 2011-09-24 18:12:21
compartment [Compartment:7660] nucleoplasm
goCellularComponent [GO_CellularComponent:17169] DNA replication factor A complex
hasComponent
modified [InstanceEdit:75992] Matthews, L, 2003-09-10 06:00:00 [InstanceEdit:83604] Matthews, L, 2003-11-23 12:20:00 [InstanceEdit:109937] Gopinathrao, G, 2004-01-22 20:43:32 [InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32 [InstanceEdit:110546] Gopinathrao, G, 2004-02-02 17:30:34 [InstanceEdit:112170] Matthews, L, 0000-00-00 00:00:00 [InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06 [InstanceEdit:1606718] D'Eustachio, P, 2011-09-24 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name RPA heterotrimer
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:366674] R-HSA-68462.19
(hasComponent) [Complex:68463] Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] [Homo sapiens] [Complex:75993] RPA-coated 3'-ends of DNA double strand break [nucleoplasm] [Homo sapiens] [Complex:83618] RAD51:RPA complex [nucleoplasm] [Homo sapiens] [Complex:83620] RAD52:RPA complex [nucleoplasm] [Homo sapiens] [Complex:109941] pre-incision complex in GG-NER [nucleoplasm] [Homo sapiens] [Complex:109945] pre-incision complex with open DNA bubble [nucleoplasm] [Homo sapiens] [Complex:109947] Incision complex with 3'-incised damaged DNA [nucleoplasm] [Homo sapiens] [Complex:174436] Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] [Homo sapiens] [Complex:176293] RPA complexed to ssDNA [nucleoplasm] [Homo sapiens] [Complex:912428] Meiotic Holliday Junction [nucleoplasm] [Homo sapiens]
(inferredFrom) [Complex:1115047] RPA heterotrimer (name copied from entity in Homo sapiens) [nucleoplasm] [Oryza sativa]
(input) [Reaction:69140] RPA binds to the Flap [Homo sapiens] [Reaction:109969] Repair synthesis of patch ~27-30 bases long by DNA Pol Delta [Homo sapiens] [Reaction:174445] RPA binds to the Flap on the C-strand [Homo sapiens] [Reaction:176175] Stalling of DNA replication fork and RPA binding [Homo sapiens] [BlackBoxEvent:912503] Formation of meiotic single-stranded DNA invasion complex [Homo sapiens] [Reaction:5333051] RPA1 binds HSF1 [Homo sapiens] [BlackBoxEvent:5358599] EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch [Homo sapiens] [BlackBoxEvent:5358619] EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL) [Homo sapiens] [Reaction:5689317] Formation of the pre-incision complex in GG-NER [Homo sapiens] [Reaction:5693542] Association of RPA complexes with ssDNA at resected DNA DSBs [Homo sapiens]
(output) [Reaction:69144] Removal of RNA primer and dissociation of RPA and Dna2 [Homo sapiens] [Reaction:109969] Repair synthesis of patch ~27-30 bases long by DNA Pol Delta [Homo sapiens] [Reaction:174441] Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand [Homo sapiens] [BlackBoxEvent:912429] Resolution of meiotic holliday junction [Homo sapiens] [Reaction:5358579] DNA polymerase delta polymerizes DNA across single stranded gap [Homo sapiens] [Reaction:5687758] PPP4C:PPP4R2 dephosphorylates RPA2 [Homo sapiens]
(regulator) [PositiveRegulation:5333056] Positive regulation by 'RPA heterotrimer [nucleoplasm]'
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No pathways have been reviewed or authored by RPA heterotrimer [nucleoplasm] (68462)