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Details on Person RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]

Class:IdComplex:6814534
_displayNameRNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]
_timestamp2016-02-19 18:12:35
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:6814532] May, Bruce, 2015-11-27
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:6814871] Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B
[LiteratureReference:6814866] RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation
[LiteratureReference:6810207] Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes
[LiteratureReference:6814900] The Integrator complex controls the termination of transcription at diverse classes of gene targets
[LiteratureReference:6807404] The little elongation complex functions at initiation and elongation phases of snRNA gene transcription
modified[InstanceEdit:6814922] May, Bruce, 2015-11-29
nameRNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:Pre-snRNA:RNU1-1,RNU2-1 gene:TBP:TFIIB:TFIIA:TFIIF:snTAFc:CDK7:SNAPc:POU2F1:ZNF143
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8859080] R-HSA-6814534.1
(input)[BlackBoxEvent:6814559] Pre-snRNA is elongated and capped with 7-methylguanosine [Homo sapiens]
(output)[BlackBoxEvent:6814549] Pre-snRNA transcript initiation, Integrator binding, LEC binding [Homo sapiens]
(physicalEntity)[CatalystActivity:6814553] protein serine/threonine phosphatase activity of RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]
[CatalystActivity:6814557] protein serine/threonine kinase activity of RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]
[CatalystActivity:6814886] DNA-directed RNA polymerase activity of RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]
(regulator)[Requirement:9685235] Requirement by 'RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]'
[Requirement:9685236] Requirement by 'RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]'
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No pathways have been reviewed or authored by RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (6814534)