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Details on Person PNPLA6 hydrolyzes LysoPtdCho

Class:IdReaction:6814254
_displayNamePNPLA6 hydrolyzes LysoPtdCho
_doReleaseTRUE
_timestamp2016-02-19 18:19:41
authored[InstanceEdit:6814856] D'Eustachio, Peter, 2015-11-28
catalystActivity[CatalystActivity:6814255] phosphatidylcholine lysophospholipase A1 activity of PNPLA6 [endoplasmic reticulum membrane]
catalystActivityReference[CatalystActivityReference:9643669] lysophospholipase activity of PNPLA6 [endoplasmic reticulum membrane] Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells
compartment[Compartment:12045] endoplasmic reticulum membrane
[Compartment:70101] cytosol
created[InstanceEdit:6814248] D'Eustachio, Peter, 2015-11-25
edited[InstanceEdit:6814856] D'Eustachio, Peter, 2015-11-28
input[SimpleEntity:6814253] LysoPtdCho [endoplasmic reticulum membrane]
[SimpleEntity:29356] H2O [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:6814246] Neuropathy target esterase catalyzes osmoprotective renal synthesis of glycerophosphocholine in response to high NaCl
[LiteratureReference:6814251] Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells
[LiteratureReference:6814257] Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells
modified[InstanceEdit:6814259] D'Eustachio, Peter, 2015-11-25
[InstanceEdit:8847429] D'Eustachio, Peter, 2015-11-30
[InstanceEdit:8847431] D'Eustachio, Peter, 2015-11-30
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePNPLA6 hydrolyzes LysoPtdCho
output[SimpleEntity:1498750] GPCho [cytosol]
[SimpleEntity:1524021] LCFA(-) [endoplasmic reticulum membrane]
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8847421] Jassal, Bijay, 2015-11-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8860971] R-HSA-6814254.3
summation[Summation:6814245] PNPLA6 (Patatin-like phospholipase domain-containing protein...
(hasEvent)[Pathway:6814848] Glycerophospholipid catabolism [Homo sapiens]
(precedingEvent)[Reaction:6814132] GDPD5 hydrolyzes GPCho [Homo sapiens]
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No pathways have been reviewed or authored by PNPLA6 hydrolyzes LysoPtdCho (6814254)