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Details on Person Orlic-Milacic, Marija, 2015-11-17
| Class:Id | InstanceEdit:6810440 |
| _displayName | Orlic-Milacic, Marija, 2015-11-17 |
| _timestamp | 2015-11-17 05:06:57 |
| author | [Person:1169272] Orlic-Milacic, Marija |
| dateTime | 2015-11-17 10:06:36 |
| (created) | [BlackBoxEvent:6810441] (NEW)TP53 family members stimulate BBC3 (PUMA) expression [Homo sapiens] [Reaction:6810442] (NEW)TP53 family members bind the BBC3 (PUMA) promoter [Homo sapiens] [Complex:6810443] (NEW)(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 Gene [nucleoplasm] [Homo sapiens] |
| (modified) | [BlackBoxEvent:139913] TP53 stimulates BBC3 (PUMA) expression [Homo sapiens] [Pathway:139915] Activation of PUMA and translocation to mitochondria [Homo sapiens] [PositiveGeneExpressionRegulation:159038] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:PMAIP1 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:159040] Positive gene expression regulation by '(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 Gene [nucleoplasm]' [PathwayDiagram:450953] Diagram of Intrinsic Pathway for Apoptosis and Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function [Summation:4331330] TP53 (p53) binds the promoter of the PMAIP1 (NOXA) gene to i... [Reaction:4331331] TP53 binds the PMAIP1 (NOXA) promoter [Homo sapiens] [Complex:4331332] p-S15,S20-TP53 Tetramer:PMAIP1 Gene [nucleoplasm] [Homo sapiens] [Reaction:4331340] TP53 binds the BBC3 (PUMA) promoter [Homo sapiens] [Complex:4331345] (p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 Gene [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2015-11-17 (6810440)