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Details on Person Orlic-Milacic, Marija, 2015-11-17

Class:IdInstanceEdit:6810440
_displayNameOrlic-Milacic, Marija, 2015-11-17
_timestamp2015-11-17 05:06:57
author[Person:1169272] Orlic-Milacic, Marija
dateTime2015-11-17 10:06:36
(created)[BlackBoxEvent:6810441] (NEW)TP53 family members stimulate BBC3 (PUMA) expression [Homo sapiens]
[Reaction:6810442] (NEW)TP53 family members bind the BBC3 (PUMA) promoter [Homo sapiens]
[Complex:6810443] (NEW)(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 Gene [nucleoplasm] [Homo sapiens]
(modified)[BlackBoxEvent:139913] TP53 stimulates BBC3 (PUMA) expression [Homo sapiens]
[Pathway:139915] Activation of PUMA and translocation to mitochondria [Homo sapiens]
[PositiveGeneExpressionRegulation:159038] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:PMAIP1 Gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:159040] Positive gene expression regulation by '(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 Gene [nucleoplasm]'
[PathwayDiagram:450953] Diagram of Intrinsic Pathway for Apoptosis and Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
[Summation:4331330] TP53 (p53) binds the promoter of the PMAIP1 (NOXA) gene to i...
[Reaction:4331331] TP53 binds the PMAIP1 (NOXA) promoter [Homo sapiens]
[Complex:4331332] p-S15,S20-TP53 Tetramer:PMAIP1 Gene [nucleoplasm] [Homo sapiens]
[Reaction:4331340] TP53 binds the BBC3 (PUMA) promoter [Homo sapiens]
[Complex:4331345] (p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 Gene [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2015-11-17 (6810440)