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Details on Person HOXB2 chromatin is activated

Class:IdBlackBoxEvent:6810159
_displayNameHOXB2 chromatin is activated
_doReleaseTRUE
_timestamp2015-11-20 15:12:32
authored[InstanceEdit:5617432] May, Bruce, 2014-08-07
[InstanceEdit:6810137] Rezsohazy, René, 2015-11-15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:6810152] May, Bruce, 2015-11-15
edited[InstanceEdit:6810149] May, Bruce, 2015-11-15
inferredFrom
input[Complex:5617482] HOXB2 bivalent chromatin [nucleoplasm] [Homo sapiens]
[DefinedSet:5619379] MLL3,4 complex [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:4687099] A histone H3 lysine 27 demethylase regulates animal posterior development
[LiteratureReference:4687095] Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
modified[InstanceEdit:6810172] May, Bruce, 2015-11-15
[InstanceEdit:6810187] May, Bruce, 2015-11-16
[InstanceEdit:6810603] Matthews, Lisa, 2015-11-18
[InstanceEdit:6810604] Matthews, Lisa, 2015-11-18
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameHOXB2 chromatin is activated
output[Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens]
[Complex:6810166] HOXB2 active chromatin [nucleoplasm] [Homo sapiens]
regulatedBy[PositiveRegulation:6810167] Positive regulation by 'atRA [nucleoplasm]'
regulationReference[RegulationReference:9642111] Positive regulation by 'atRA [nucleoplasm]' A histone H3 lysine 27 demethylase regulates animal posterior development
releaseDate2015-12-15
releaseStatusNEW
reviewed[InstanceEdit:5693642] Blasi, F, 2015-05-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6812631] R-HSA-6810159.4
summation[Summation:6810156] During activation of HOXB1 by retinoic acid in human embryon...
(hasEvent)[Pathway:5617472] Activation of anterior HOX genes in hindbrain development during early embryogenesis [Homo sapiens]
(precedingEvent)[BlackBoxEvent:5617492] EGR2 (KROX20) activates HOXB2 expression [Homo sapiens]
[BlackBoxEvent:5621002] HOXB1 activates HOXB2 expression [Homo sapiens]
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