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Details on Person DDO oxidizes D-Asp to OA
Class:Id Reaction:6810076
_displayName DDO oxidizes D-Asp to OA
_doRelease TRUE
_timestamp 2024-12-04 22:39:51
authored [InstanceEdit:6813606] D'Eustachio, Peter, 2015-11-20
catalystActivity [CatalystActivity:6810051] D-aspartate oxidase activity of DDO:FAD [peroxisomal matrix]
catalystActivityReference [CatalystActivityReference:9643124] D-aspartate oxidase activity of DDO:FAD [peroxisomal matrix] Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes
compartment [Compartment:17951] peroxisomal matrix
created [InstanceEdit:6810066] D'Eustachio, Peter, 2015-11-14
crossReference [DatabaseIdentifier:9930619] RHEA:12513
edited [InstanceEdit:6813606] D'Eustachio, Peter, 2015-11-20
input [SimpleEntity:6810061] D-Asp [peroxisomal matrix] [SimpleEntity:141343] H2O [peroxisomal matrix] [SimpleEntity:113535] O2 [peroxisomal matrix]
isChimeric FALSE
literatureReference [LiteratureReference:6810054] C-terminal tripeptide Ser-Asn-Leu (SNL) of human D-aspartate oxidase is a functional peroxisome-targeting signal [LiteratureReference:6810049] Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes [LiteratureReference:6810075] Thiolactomycin inhibits D-aspartate oxidase: a novel approach to probing the active site environment [LiteratureReference:6810072] The primary structure of the flavoprotein D-aspartate oxidase from beef kidney [LiteratureReference:6810057] Structural and functional characterization of the human brain D-aspartate oxidase
modified [InstanceEdit:6813606] D'Eustachio, Peter, 2015-11-20 [InstanceEdit:8847448] D'Eustachio, Peter, 2015-11-30 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9930615] D'Eustachio, Peter, 2024-12-04
name DDO oxidizes D-Asp to OA D-aspartate + H2O + O2 => H2O2 + NH4(+) + oxaloacetate
output [SimpleEntity:6810070] OA [peroxisomal matrix] [SimpleEntity:389843] NH4+ [peroxisomal matrix] [SimpleEntity:113575] H2O2 [peroxisomal matrix]
releaseDate 2016-03-23
releaseStatus NEW
reviewed [InstanceEdit:8847449] Jassal, Bijay, 2015-11-30
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:8861032] R-HSA-6810076.4
summation [Summation:6810078] Peroxisomal DDO (D-aspartate oxidase) catalyzes the oxidatio...
(hasEvent) [Pathway:389661] Glyoxylate metabolism and glycine degradation [Homo sapiens]
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