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Details on Person NUDT12 hydrolyses NADH to NMNH

Class:IdReaction:6809287
_displayNameNUDT12 hydrolyses NADH to NMNH
_doReleaseTRUE
_timestamp2025-02-11 17:23:37
authored[InstanceEdit:6809290] Jassal, Bijay, 2015-11-10
catalystActivity[CatalystActivity:6809293] NADH pyrophosphatase activity of NUDT12 [peroxisomal matrix]
compartment[Compartment:17951] peroxisomal matrix
created[InstanceEdit:6809290] Jassal, Bijay, 2015-11-10
crossReference[DatabaseIdentifier:9938250] RHEA:48869
edited[InstanceEdit:6809290] Jassal, Bijay, 2015-11-10
input[SimpleEntity:192305] NADH [peroxisomal matrix]
[SimpleEntity:141343] H2O [peroxisomal matrix]
internalReviewed[InstanceEdit:9938268] D'Eustachio, Peter, 2025-02-11
isChimericFALSE
literatureReference[LiteratureReference:6809288] Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein
modified[InstanceEdit:6809294] Jassal, Bijay, 2015-11-10
[InstanceEdit:8850394] Jassal, Bijay, 2015-12-21
[InstanceEdit:8851786] Jassal, Bijay, 2016-01-11
[InstanceEdit:8940088] Jassal, Bijay, 2016-09-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9938253] D'Eustachio, Peter, 2025-02-11
[InstanceEdit:9938269] D'Eustachio, Peter, 2025-02-11
nameNUDT12 hydrolyses NADH to NMNH
NADH + H2O => reduced beta-nicotinamide D-ribonucleotide + AMP + 2 H(+)
output[SimpleEntity:6809289] NMNH [peroxisomal matrix]
[SimpleEntity:193465] H+ [peroxisomal matrix]
[SimpleEntity:193465] H+ [peroxisomal matrix]
[SimpleEntity:389620] AMP [peroxisomal matrix]
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
reviewStatus[ReviewStatus:9821385] four stars
revised[InstanceEdit:8940089] Jassal, Bijay, 2016-09-23
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861001] R-HSA-6809287.4
structureModified[InstanceEdit:9938253] D'Eustachio, Peter, 2025-02-11
summation[Summation:6809291] The human nudix hydrolase peroxisomal NADH pyrophosphatase (...
(hasEvent)[Pathway:196807] Nicotinate metabolism [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782225] Update Tracker - [Reaction:6809287] NUDT12 hydrolyses NADH to NMNH - v59:[modifyText]
[_UpdateTracker:9939640] Update Tracker - [Reaction:6809287] NUDT12 hydrolyses NADH to NMNH - v92:[addInput, removeOutput]
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