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Details on Person EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA

Class:IdReaction:6809264
_displayNameEHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA
_doReleaseTRUE
_timestamp2024-06-20 21:37:12
authored[InstanceEdit:6809272] D'Eustachio, Peter, 2015-11-09
catalystActivity[CatalystActivity:6809275] (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity of EHHADH [peroxisomal matrix]
compartment[Compartment:17951] peroxisomal matrix
created[InstanceEdit:6809265] D'Eustachio, Peter, 2015-11-09
crossReference[DatabaseIdentifier:9914146] RHEA:78637
edited[InstanceEdit:6809272] D'Eustachio, Peter, 2015-11-09
input[SimpleEntity:390248] 3-hydroxyhexacosanoyl-CoA [peroxisomal matrix]
[SimpleEntity:192307] NAD+ [peroxisomal matrix]
literatureReference[LiteratureReference:6809258] Import of human bifunctional enzyme into peroxisomes of human hepatoma cells in vitro
[LiteratureReference:6809276] Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids
[LiteratureReference:6809271] Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids
[LiteratureReference:6809274] Induction, immunochemical identity and immunofluorescence localization of an 80 000-molecular-weight peroxisome-proliferation-associated polypeptide (polypeptide PPA-80) and peroxisomal enoyl-CoA hydratase of mouse liver and renal cortex
[LiteratureReference:6809266] Peroxisomal beta oxidation system of rat liver. Copurification of enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase
modified[InstanceEdit:8847433] D'Eustachio, Peter, 2015-11-30
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9914142] D'Eustachio, Peter, 2024-06-20
nameEHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA
3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (EHHADH)
output[SimpleEntity:390241] 3-ketohexacosanoyl-CoA [peroxisomal matrix]
[SimpleEntity:192305] NADH [peroxisomal matrix]
[SimpleEntity:193465] H+ [peroxisomal matrix]
precedingEvent
releaseDate2009-04-01
reviewed[InstanceEdit:8847434] Jassal, Bijay, 2015-11-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8860999] R-HSA-6809264.3
summation[Summation:6809269] Peroxisomal EHHADH catalyzes the reaction of 3-hydroxyhexaco...
(hasEvent)[Pathway:390247] Beta-oxidation of very long chain fatty acids [Homo sapiens]
(precedingEvent)[Reaction:390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA [Homo sapiens]
[Reaction:9856871] MDH1 reduces OA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919340] Update Tracker - [Reaction:6809264] EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA - v90:[modifyText]
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