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Details on Person EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA

Class:IdReaction:6809263
_displayNameEHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA
_doReleaseTRUE
_timestamp2024-06-20 21:37:14
authored[InstanceEdit:6809272] D'Eustachio, Peter, 2015-11-09
catalystActivity[CatalystActivity:6809277] 3-hydroxyacyl-CoA dehydratase activity of EHHADH [peroxisomal matrix]
compartment[Compartment:17951] peroxisomal matrix
created[InstanceEdit:6809265] D'Eustachio, Peter, 2015-11-09
crossReference[DatabaseIdentifier:9914121] RHEA:39213
edited[InstanceEdit:6809272] D'Eustachio, Peter, 2015-11-09
input[SimpleEntity:390249] trans-2,3-dehydrohexacosanoyl-CoA [peroxisomal matrix]
[SimpleEntity:141343] H2O [peroxisomal matrix]
literatureReference[LiteratureReference:6809258] Import of human bifunctional enzyme into peroxisomes of human hepatoma cells in vitro
[LiteratureReference:6809276] Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids
[LiteratureReference:6809271] Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids
[LiteratureReference:6809274] Induction, immunochemical identity and immunofluorescence localization of an 80 000-molecular-weight peroxisome-proliferation-associated polypeptide (polypeptide PPA-80) and peroxisomal enoyl-CoA hydratase of mouse liver and renal cortex
[LiteratureReference:6809266] Peroxisomal beta oxidation system of rat liver. Copurification of enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase
modified[InstanceEdit:8847433] D'Eustachio, Peter, 2015-11-30
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9914142] D'Eustachio, Peter, 2024-06-20
nameEHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA
(2E)-hexacosenoyl-CoA + H2O => (3R)-hydroxyhexacosanoyl-CoA
trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (EHHADH)
output[SimpleEntity:390248] 3-hydroxyhexacosanoyl-CoA [peroxisomal matrix]
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8847434] Jassal, Bijay, 2015-11-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861000] R-HSA-6809263.3
summation[Summation:6809270] Peroxisomal EHHADH catalyzes the reaction of trans-2,3-dehyd...
(hasEvent)[Pathway:390247] Beta-oxidation of very long chain fatty acids [Homo sapiens]
(precedingEvent)[Reaction:390251] HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA [Homo sapiens]
[Reaction:6809264] EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA [Homo sapiens]
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