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Details on Person MTMR7 binds MTMR9
Class:Id Reaction:6809238
_displayName MTMR7 binds MTMR9
_doRelease TRUE
_timestamp 2025-08-12 22:18:02
authored [InstanceEdit:6809880] Orlic-Milacic, Marija, 2015-11-13
catalystActivity [CatalystActivity:9947649] phosphatase activator activity of MTMR9 [cytosol]
catalystActivityReference [CatalystActivityReference:9947650] phosphatase activator activity of MTMR9 [cytosol] Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9
compartment [Compartment:70101] cytosol
created [InstanceEdit:6809245] Orlic-Milacic, Marija, 2015-11-09
edited [InstanceEdit:8959448] Orlic-Milacic, Marija, 2017-01-25
inferredFrom
input [EntityWithAccessionedSequence:1604650] MTMR7 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6809239] MTMR9 [cytosol] [Homo sapiens]
internalReviewed [InstanceEdit:9947653] D'Eustachio, Peter, 2025-05-09
isChimeric FALSE
literatureReference [LiteratureReference:1676117] Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9
modified [InstanceEdit:6809501] Orlic-Milacic, Marija, 2015-11-11 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8959445] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:8959447] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:8959448] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:8959449] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9947651] D'Eustachio, Peter, 2025-05-09 [InstanceEdit:9947654] D'Eustachio, Peter, 2025-05-09 [InstanceEdit:9962971] D'Eustachio, Peter, 2025-08-12
name MTMR7 binds MTMR9
output [Complex:6809241] MTMR7:MTMR9 [cytosol] [Homo sapiens]
previousReviewStatus [ReviewStatus:9821385] four stars
releaseDate 2017-03-27
reviewed [InstanceEdit:8959443] Rush, Mark G, 2017-01-10 [InstanceEdit:9962972] Hill, David P, 2025-08-12
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:8896517] R-HSA-6809238.4
structureModified [InstanceEdit:9947651] D'Eustachio, Peter, 2025-05-09
summation [Summation:6809242] MTMR7 binds to MTMR9, an enzymatically inactive myotubularin...
(hasEvent) [Pathway:1660517] Synthesis of PIPs at the late endosome membrane [Homo sapiens] [Pathway:1855183] Synthesis of IP2, IP, and Ins in the cytosol [Homo sapiens] [Pathway:6809305] PI5P production is facilitated by MTMR9 [Homo sapiens]
(precedingEvent) [Reaction:6809565] I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 [Homo sapiens]
(updatedInstance) [_UpdateTracker:9953753] Update Tracker - [Reaction:6809238] MTMR7 binds MTMR9 - v93:[removeCatalystActivity]
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