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Details on Person ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex

Class:IdReaction:6807875
_displayNameARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex
_doReleaseTRUE
_timestamp2016-03-17 14:43:03
authored[InstanceEdit:6793574] Rothfels, Karen, 2015-09-01
compartment[Compartment:6791047] endoplasmic reticulum-Golgi intermediate compartment membrane
created[InstanceEdit:6807874] Rothfels, Karen, 2015-11-03
edited[InstanceEdit:6793574] Rothfels, Karen, 2015-09-01
input[Complex:6807822] RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
[DefinedSet:6807832] ARFGAP1,2,3 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:5688558] PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
[DefinedSet:6807812] p24 dimers [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
[CandidateSet:6807816] ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
[DefinedSet:427190] Ankyrin [cytosol] [Homo sapiens]
[Complex:420053] Spectrin tetramer [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:6807653] Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum
[LiteratureReference:6807641] A v-SNARE implicated in intra-Golgi transport
[LiteratureReference:6807663] Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors
[LiteratureReference:6807652] Coatomer interaction with di-lysine endoplasmic reticulum retention motifs
[LiteratureReference:6804917] Live imaging of bidirectional traffic from the ERGIC
[LiteratureReference:6807674] KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET
[LiteratureReference:6807643] Bidirectional transport by distinct populations of COPI-coated vesicles
[LiteratureReference:6804910] ER-to-Golgi transport visualized in living cells
[LiteratureReference:6807709] The COPI system: molecular mechanisms and function
[LiteratureReference:6807668] Diverse roles for the p24 family of proteins in eukaryotic cells
[LiteratureReference:6807698] Recruitment to Golgi membranes of ADP-ribosylation factor 1 is mediated by the cytoplasmic domain of p23
[LiteratureReference:6805327] Coatomer, the coat protein of COPI transport vesicles, discriminates endoplasmic reticulum residents from p24 proteins
[LiteratureReference:6805294] A single binding site for dilysine retrieval motifs and p23 within the gamma subunit of coatomer
[LiteratureReference:6807638] A conformational change in the alpha-subunit of coatomer induced by ligand binding to gamma-COP revealed by single-pair FRET
[LiteratureReference:6807695] Receptor-induced polymerization of coatomer
[LiteratureReference:6807682] Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane
[LiteratureReference:5689381] Selective export of human GPI-anchored proteins from the endoplasmic reticulum
[LiteratureReference:6807689] Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking
[LiteratureReference:3247709] p24 proteins are required for secretion of Wnt ligands
[LiteratureReference:6807649] Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain
[LiteratureReference:6807666] Decoding of sorting signals by coatomer through a GTPase switch in the COPI coat complex
[LiteratureReference:6804887] ARF proteins: roles in membrane traffic and beyond
[LiteratureReference:6807707] Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1
[LiteratureReference:6808358] Arf GAP2 is positively regulated by coatomer and cargo
[LiteratureReference:6808324] Two human ARFGAPs associated with COP-I-coated vesicles
[LiteratureReference:5246472] Functional characterization of novel human ARFGAP3
[LiteratureReference:6808352] Consensus nomenclature for the human ArfGAP domain-containing proteins
[LiteratureReference:200545] Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature
[LiteratureReference:6808316] Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature
[LiteratureReference:6808356] Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking
[LiteratureReference:6808345] Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat
[LiteratureReference:6808330] The KDEL receptor, ERD2, regulates intracellular traffic by recruiting a GTPase-activating protein for ARF1
[LiteratureReference:6808934] Na,K-ATPase transport from endoplasmic reticulum to Golgi requires the Golgi spectrin-ankyrin G119 skeleton in Madin Darby canine kidney cells
[LiteratureReference:6808915] ADP ribosylation factor regulates spectrin binding to the Golgi complex
[LiteratureReference:6808927] Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles
[LiteratureReference:6808940] beta III spectrin binds to the Arp1 subunit of dynactin
modified[InstanceEdit:6809016] Rothfels, Karen, 2015-11-09
[InstanceEdit:6809415] Rothfels, Karen, 2015-11-11
[InstanceEdit:6810507] Rothfels, Karen, 2015-11-17
[InstanceEdit:6810542] Rothfels, Karen, 2015-11-17
[InstanceEdit:8864992] Rothfels, Karen, 2016-03-17
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex
output[Complex:6807825] RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
precedingEvent
releaseDate2015-12-15
releaseStatusNEW
reviewed[InstanceEdit:6793638] Gillespie, Marc E, 2015-09-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6812510] R-HSA-6807875.3
summation[Summation:6807720] Binding and polymerization of the coatomer (the COPI coat) i...
(hasEvent)[Pathway:6807878] COPI-mediated anterograde transport [Homo sapiens]
(precedingEvent)[Reaction:6807877] ARFGAPs stimulate ARF GTPase activity [Homo sapiens]
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