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Details on Person CYB5Rs reduce MetHb to HbA

Class:IdReaction:6806831
_displayNameCYB5Rs reduce MetHb to HbA
_doReleaseTRUE
_timestamp2017-12-20 12:04:30
authored[InstanceEdit:6806828] Jassal, Bijay, 2015-10-26
catalystActivity[CatalystActivity:6806867] cytochrome-b5 reductase activity, acting on NAD(P)H of CYB5Rs [endoplasmic reticulum membrane]
compartment[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:6806828] Jassal, Bijay, 2015-10-26
edited[InstanceEdit:6806828] Jassal, Bijay, 2015-10-26
input[Complex:9033251] MetHb [cytosol] [Homo sapiens]
[SimpleEntity:73473] NADH [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:6806857] Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells
[LiteratureReference:6806871] Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa
[LiteratureReference:6806866] NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum
modified[InstanceEdit:6806848] Jassal, Bijay, 2015-10-27
[InstanceEdit:6806924] Jassal, Bijay, 2015-10-28
[InstanceEdit:8847692] Jassal, Bijay, 2015-12-02
[InstanceEdit:8847696] Jassal, Bijay, 2015-12-02
[InstanceEdit:8850389] Jassal, Bijay, 2015-12-21
[InstanceEdit:8851670] Jassal, Bijay, 2016-01-08
[InstanceEdit:8851786] Jassal, Bijay, 2016-01-11
[InstanceEdit:8862020] Jassal, Bijay, 2016-02-24
[InstanceEdit:9033254] Jassal, Bijay, 2017-12-20
[InstanceEdit:9033259] Jassal, Bijay, 2017-12-20
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCYB5Rs reduce MetHb to HbA
output[Complex:9033252] HbA [cytosol] [Homo sapiens]
[SimpleEntity:29360] NAD+ [cytosol]
[SimpleEntity:70106] H+ [cytosol]
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861082] R-HSA-6806831.3
summation[Summation:6806830] NADH-Cytochrome b5 reductases (CYB5Rs), flavoproteins consis...
(hasEvent)[Pathway:1237044] Erythrocytes take up carbon dioxide and release oxygen [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780107] Update Tracker - [Reaction:6806831] CYB5Rs reduce MetHb to HbA - v64:[add_removeInput, add_removeOutput, modifyText]
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No pathways have been reviewed or authored by CYB5Rs reduce MetHb to HbA (6806831)