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Details on Person Secondary (specific) granules are peroxidase-negative and ri...
| Class:Id | Summation:6806048 |
|---|---|
| _displayName | Secondary (specific) granules are peroxidase-negative and ri... |
| _timestamp | 2015-10-21 15:59:20 |
| created | [InstanceEdit:6806061] Jupe, Steve, 2015-10-21 |
| literatureReference | [LiteratureReference:6806068] The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes [LiteratureReference:6806078] The development of neutrophilic polymorphonuclear leukocytes in human bone marrow [LiteratureReference:6806072] Granules of the human neutrophilic polymorphonuclear leukocyte [LiteratureReference:6806046] Isolation and characterization of gelatinase granules from human neutrophils |
| text | Secondary (specific) granules are peroxidase-negative and rich in antimicrobial substances (Joiner et al. 1989, Rorvig et al. 2012). They are more irregular and elongated in form than azurophil granules (Bainton et al. 1971). This might reflect volume adjustment in azurophil granules, which are known to proteolytically process a significant fraction of the proteins that are targeted to them, while little or no processing and therefore no increase in osmotic activity due to proteolysis has been observed in secondary granules (Borregaard & Cowland 1997). Secondary and tertiary granules have overlapping contents but can be discriminated by their intrinsic buoyant densities when centrifuged on gradient media (Kjeldsen et al. 1994). |
| (summation) | [Reaction:6798749] Exocytosis of specific granule lumen proteins [Homo sapiens] |
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No pathways have been reviewed or authored by Secondary (specific) granules are peroxidase-negative and ri... (6806048)
