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Details on Person AMPK phosphorylates TP53

Class:IdReaction:6805470
_displayNameAMPK phosphorylates TP53
_doReleaseTRUE
_timestamp2017-02-23 16:05:06
authored[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
catalystActivity[CatalystActivity:6805465] AMP-activated protein kinase activity of Activated AMPK heterotrimer [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:6805464] Orlic-Milacic, Marija, 2015-10-19
edited[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input[Complex:3209194] TP53 Tetramer [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:6805462] AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
[LiteratureReference:8856545] AMPK couples p73 with p53 in cell fate decision
modified[InstanceEdit:8856550] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8856588] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8979252] Orlic-Milacic, Marija, 2017-02-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAMPK phosphorylates TP53
output[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[Complex:349474] p-S15-TP53 Tetramer [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
[InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861051] R-HSA-6805470.3
summation[Summation:6805469] AMPK, activated in response to glucose deprivation, phosphor...
(hasEvent)[Pathway:6804756] Regulation of TP53 Activity through Phosphorylation [Homo sapiens]
(precedingEvent)[Reaction:6805285] PLK3 phosphorylates TP53 [Homo sapiens]
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No pathways have been reviewed or authored by AMPK phosphorylates TP53 (6805470)