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Details on Person Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
| Class:Id | LiteratureReference:6805257 |
|---|---|
| _displayName | Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration |
| _timestamp | 2015-10-19 16:23:54 |
| author | [Person:6805258] Patrick, G N [Person:6805267] Zukerberg, L [Person:6805260] Nikolic, M [Person:6805270] de la Monte, S [Person:6805272] Dikkes, P [Person:6805254] Tsai, L H |
| created | [InstanceEdit:6805264] Orlic-Milacic, Marija, 2015-10-19 |
| journal | Nature |
| pages | 615-22 |
| pubMedIdentifier | 10604467 |
| title | Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration |
| volume | 402 |
| year | 1999 |
| (literatureReference) | [Reaction:6805276] CDK5 phosphorylates TP53 [Homo sapiens] [Reaction:8863013] CDK5 binds p25 [Homo sapiens] [Reaction:8863587] CDK5:p25 translocates to the nucleus [Homo sapiens] [Summation:8863459] p25 has a 5-10 fold longer half-life compared to p35 and lac... [Summation:8863592] The complex of CDK5 and p25 can translocate to the nucleus (... |
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