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Details on Person CK2:FACT phosphorylates TP53

Class:IdReaction:6805059
_displayNameCK2:FACT phosphorylates TP53
_doReleaseTRUE
_timestamp2017-02-23 16:21:40
authored[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
catalystActivity[CatalystActivity:6805058] protein serine/threonine kinase activity of CK2:FACT [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:6805049] Orlic-Milacic, Marija, 2015-10-16
edited[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input[Complex:3222171] p-S15,S20-TP53 Tetramer [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:6805051] A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1
[LiteratureReference:6805050] p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex
modified[InstanceEdit:8856532] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8856588] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8979254] Orlic-Milacic, Marija, 2017-02-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCK2:FACT phosphorylates TP53
output[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[Complex:6805046] p-S15,S20,S392-TP53 Tetramer [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
[InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861043] R-HSA-6805059.3
summation[Summation:6805069] Casein kinase II (CK2), associated with the FACT2 complex, p...
(hasEvent)[Pathway:6804756] Regulation of TP53 Activity through Phosphorylation [Homo sapiens]
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No pathways have been reviewed or authored by CK2:FACT phosphorylates TP53 (6805059)