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Query author contributions in Reactome

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Details on Person p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm]

Class:IdDefinedSet:6804745
_displayNamep-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm]
_timestamp2016-07-29 17:30:54
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:6804733] Orlic-Milacic, Marija, 2015-10-14
hasMember
literatureReference[LiteratureReference:6804747] Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage
[LiteratureReference:6804738] Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability
[LiteratureReference:6804740] The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo
modified[InstanceEdit:6804943] Orlic-Milacic, Marija, 2015-10-15
[InstanceEdit:8862012] Orlic-Milacic, Marija, 2016-02-23
[InstanceEdit:8932867] Orlic-Milacic, Marija, 2016-07-29
namep-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8858893] R-HSA-6804745.2
(hasComponent)[Complex:6804885] p-S166,S188-MDM2 dimer, p-S166,S188-MDM2,MDM4:TP53 [nucleoplasm] [Homo sapiens]
[Complex:6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm] [Homo sapiens]
(input)[Reaction:5633460] MDM2 binds TP53 [Homo sapiens]
(output)[Reaction:6804741] MDM2 forms homo- or heterodimers [Homo sapiens]
[Reaction:6804879] MDM2 ubiquitinates TP53 [Homo sapiens]
(physicalEntity)[CatalystActivity:6798364] ubiquitin protein ligase activity of p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm]
(updatedInstance)[_UpdateTracker:9894780] Update Tracker - [DefinedSet:6804745] p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] - v58:[add_removeHasMember, modifyName]
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No pathways have been reviewed or authored by p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] (6804745)
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