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Details on Person TP53 in complex with ZNF385A binds the CDKN1A promoter

Class:Id	Reaction:6803801
_displayName	TP53 in complex with ZNF385A binds the CDKN1A promoter
_doRelease	TRUE
_timestamp	2016-02-19 18:20:24
authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15 [InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6803800] Orlic-Milacic, Marija, 2015-10-07
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input	[EntityWithAccessionedSequence:3786256] CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:6803718] p-S15,S20-TP53 Tetramer:ZNF385A [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:69405] WAF1, a potential mediator of p53 tumor suppression. [LiteratureReference:6803710] Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation [LiteratureReference:8856089] p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage
modified	[InstanceEdit:6803804] Orlic-Milacic, Marija, 2015-10-07 [InstanceEdit:6804126] Orlic-Milacic, Marija, 2015-10-08 [InstanceEdit:6809228] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809229] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809236] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6810438] Orlic-Milacic, Marija, 2015-11-17 [InstanceEdit:8856088] Orlic-Milacic, Marija, 2016-02-08 [InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 in complex with ZNF385A binds the CDKN1A promoter
output	[Complex:6803802] p-S15,S20-TP53 Tetramer:ZNF385A:CDKN1A Gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:6803719] TP53 binds ZNF385A [Homo sapiens] [BlackBoxEvent:6803437] TP53 stimulates ZNF385A transcription [Homo sapiens] [Reaction:6799246] CHEK1 phosphorylates TP53 [Homo sapiens] [Reaction:69685] CHEK2 phosphorylates TP53 [Homo sapiens] [Reaction:6805285] PLK3 phosphorylates TP53 [Homo sapiens]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03 [InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:6803794] Orlic-Milacic, Marija, 2015-10-07
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861069] R-HSA-6803801.2
summation	[Summation:6804124] TP53 (p53) binds at least two p53 response elements in the p...
(hasEvent)	[Pathway:69895] Transcriptional activation of cell cycle inhibitor p21 [Homo sapiens] [Pathway:6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:6803388] TP53 stimulates CDKN1A (p21) transcription [Homo sapiens]
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No pathways have been reviewed or authored by TP53 in complex with ZNF385A binds the CDKN1A promoter (6803801)