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Details on Person NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P

Class:Id	Reaction:6803771
_displayName	NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P
_doRelease	TRUE
_timestamp	2016-02-19 18:20:23
authored	[InstanceEdit:6803744] Jassal, Bijay, 2015-10-07
catalystActivity	[CatalystActivity:6803787] N-acetylglucosamine kinase activity of NAGK dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6803744] Jassal, Bijay, 2015-10-07
edited	[InstanceEdit:6803744] Jassal, Bijay, 2015-10-07
input	[DefinedSet:6803785] GlcNAc, GlcNGc [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:6803770] Structures of human N-Acetylglucosamine kinase in two complexes with N-Acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation [LiteratureReference:6803775] Molecular cloning and characterization of murine and human N-acetylglucosamine kinase [LiteratureReference:6803773] Biomedical differences between human and nonhuman hominids: potential roles for uniquely human aspects of sialic acid biology
modified	[InstanceEdit:6803806] Jassal, Bijay, 2015-10-07 [InstanceEdit:8851786] Jassal, Bijay, 2016-01-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P
output	[DefinedSet:6803738] GlcNAc-6-P, GlcNGc-6-P [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:6803761] RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc [Homo sapiens] [Reaction:4085217] NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate [Homo sapiens]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861066] R-HSA-6803771.2
summation	[Summation:6803737] Humans are not able to catalyse the formation of N-glycolyln...
(hasEvent)	[Pathway:446210] Synthesis of UDP-N-acetyl-glucosamine [Homo sapiens]
(precedingEvent)	[Reaction:6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA [Homo sapiens]
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No pathways have been reviewed or authored by NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (6803771)